Current and potential drugs for treatment of obesity

GA Bray, FL Greenway - Endocrine reviews, 1999 - academic.oup.com
A. Peripherally acting agents B. Centrally acting agents IV. Drugs That Alter Metabolism A.
Preabsorptive agents B. Postabsorptive modifiers of nutrient metabolism V. Drugs That …

The lateral hypothalamic area revisited: ingestive behavior

LL Bernardis, LL Bellinger - Neuroscience & Biobehavioral Reviews, 1996 - Elsevier
This article discusses the role of the lateral hypothalamic area (LHA) in feeding and drinking
and draws on data obtained from lesion and stimulation studies and neurochemical and …

Opioid peptides and the control of human ingestive behaviour

MR Yeomans, RW Gray - Neuroscience & Biobehavioral Reviews, 2002 - Elsevier
A variety of evidence suggests that endogenous opioid peptides play a role in the short-term
control of eating. More recently, opioid receptor antagonists like naltrexone have been …

Taste responses and preferences for sweet high-fat foods: evidence for opioid involvement

A Drewnowski, DD Krahn, MA Demitrack, K Nairn… - Physiology & …, 1992 - Elsevier
Preferences and cravings for sweet high-fat foods observed among obese and bulimic
patients may involve the endogenous opioid peptide system. The opioid antagonist …

Enhancement of naloxone penetration through human skin in vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amides

BJ Aungst, NJ Rogers, E Shefter - International journal of pharmaceutics, 1986 - Elsevier
Human skin permeation of naloxone was examined in vitro using various vehicles and
penetration enhancers. To screen various chemicals as penetration enhancers propylene …

The anorexia of aging

C MacIntosh, JE Morley, IM Chapman - Nutrition, 2000 - Elsevier
In the past 100 y, there has been a dramatic increase in the number and proportion of
people living into old age in Western countries. The proportion of the population that is …

Naloxone

KA Handal, JL Schauben, FR Salamone - Annals of emergency medicine, 1983 - Elsevier
Naloxone hydrochloride, a synthetic N-allyl derivative of oxymorphone, is an effective agent
for the reversal of the cardiovascular and respiratory depression associated with narcotic …

Effects of naltrexone on food intake and changes in subjective appetite during eating: evidence for opioid involvement in the appetizer effect

MR Yeomans, RW Gray - Physiology & behavior, 1997 - Elsevier
Yeomans, MR and RW Gray. Effects of naltrexone on food intake and changes in subjective
appetite during eating: evidence for opioid involvement in the appetizer effect. Physiol …

Food cravings, endogenous opioid peptides, and food intake: a review

ME Mercer, MD HOLDER - Appetite, 1997 - Elsevier
Extensive research indicates a strong relationship between endogenous opioid peptides
(EOPs) and food intake. In the present paper, we propose that food cravings act as an …

Effect of a tricyclic antidepressant and opiate antagonist on binge-eating behavior in normoweight bulimic and obese, binge-eating subjects

SA Alger, MD Schwalberg, JM Bigaouette… - The American journal of …, 1991 - Elsevier
ABSTRACT A subset of the obese population (25–30%) has been reported to engage in
binge eating at least twice weekly (bingers) and to exhibit personality traits and food …