H Nishizawa, M Yamanaka, K Igarashi - The FEBS journal, 2023 - Wiley Online Library
Ferroptosis is triggered by a chain of intracellular labile iron‐dependent peroxidation of cell membrane phospholipids. Ferroptosis is important not only as a cause of ischaemic and …
A plethora of studies indicate that iron metabolism is dysregulated in Parkinson's disease (PD). The literature reveals well-documented alterations consistent with established dogma …
D Coradduzza, A Congiargiu, Z Chen, A Zinellu… - International Journal of …, 2023 - mdpi.com
Senescence is a cellular aging process in all multicellular organisms. It is characterized by a decay in cellular functions and proliferation, resulting in increased cellular damage and …
Z Gao, Z Chen, Z Xiong, X Liu - Experimental gerontology, 2022 - Elsevier
Osteoporosis is a bone metabolic disease characterized by reduced bone mass and deterioration of bone tissue microarchitecture, leading to enhanced skeletal fragility and …
H Zheng, L Jiang, T Tsuduki, M Conrad, S Toyokuni - Redox biology, 2021 - Elsevier
Ferroptosis is a form of regulated cell necrosis, as a consequence of Fe (II)-dependent lipid peroxidation. Although ferroptosis has been linked to cancer cell death, neurodegeneration …
K Liu, L Huang, S Qi, S Liu, W Xie, L Du… - Advanced …, 2023 - Wiley Online Library
Ferroptosis is a non‐apoptotic programmed cell death caused by the accumulation of lipid peroxide. System Xc‐/glutathione peroxidase 4 (GPX4) axis and iron axis are two main …
M Mazhar, AU Din, H Ali, G Yang, W Ren, L Wang… - Cell Death …, 2021 - nature.com
Life is indeed continuously going through the irreversible and inevitable process of aging. The rate of aging process depends on various factors and varies individually. These factors …
K Igarashi, H Nishizawa, Y Saiki… - Journal of Biological …, 2021 - ASBMB
The progression of cancer involves not only the gradual evolution of cells by mutations in DNA but also alterations in the gene expression induced by those mutations and input from …