The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

Lithium has literally been everywhere forever, since it is one of the three elements created in
the Big Bang. Lithium concentration in rocks, soil, and fresh water is highly variable from …

Mitochondrial carriers facilitate the transfer of small molecules across the inner
mitochondrial membrane (IMM) to support mitochondrial function and core cellular …

Mitochondrial Ca 2+ transient is the earliest discovered organellar Ca 2+ signaling pathway.
It consist of a Ca 2+ influx, mediated by mitochondrial Ca 2+ uniporter (MCU), and …

Abstract Structure-dynamic analysis of archaeal NCX (NCX_Mj) provided new insights into
the underlying mechanisms of ion selectivity, ion-coupled alternating access, ion occlusion …

The plasma-membrane homeostasis Na+/Ca2+ exchangers (NCXs) mediate Ca2+
extrusion/entry to dynamically shape Ca2+ signaling/in biological systems ranging from …

The plasma membrane (NCX) and mitochondrial (NCLX) Na+/Ca 2+ exchangers are
structurally related proteins, although they operate under strictly different ionic conditions …

The membrane-bound sodium–calcium exchanger (NCX) proteins shape Ca2+
homeostasis in many cell types, thus participating in a wide range of physiological and …

Membrane transporters allow the selective transport of otherwise poorly permeable solutes
across the cell membrane and thus, play a key role in maintaining cellular homeostasis in all …

The mitochondria is a major hub for cellular Ca 2+ signaling. The identification of MCU, the
mitochondrial Ca 2+ influx mediator, and the mitochondrial Ca 2+ extruder NCLX, were …