Multidrug-resistant tuberculosis: latest opinions on epidemiology, rapid diagnosis and management

PS Nyasulu, CO Doumbia, V Ngah… - Current Opinion in …, 2024 - journals.lww.com
To effectively manage MDR-TB and its co-morbidity with HIV/AIDS, proactive screening
programs are imperative. The review highlights the necessity of active follow-up strategies to …

First and second-line anti-tuberculosis drug-resistance patterns in pulmonary tuberculosis patients in Zambia

N Monde, M Munyeme, G Chongwe, JJ Wensman… - Antibiotics, 2023 - mdpi.com
Background: Drug-resistant tuberculosis has continued to be a serious global health threat
defined by complexity as well as higher morbidity and mortality wherever it occurs, Zambia …

Characteristics of TB/HIV co-infection and patterns of multidrug-resistance tuberculosis in the Northwest Amhara, Ethiopia

A Seid, Y Girma, A Abebe, E Dereb… - Infection and Drug …, 2023 - Taylor & Francis
Background Multidrug-resistant tuberculosis (MDR-TB) has continued to be a serious public
health threat and significantly challenges global TB control and prevention efforts, where the …

Mycobacterium tuberculosis Sub-Lineage 4.2.2/SIT149 as Dominant Drug-Resistant Clade in Northwest Ethiopia 2020–2022: In-silico Whole-Genome Sequence …

D Mekonnen, A Munshea, E Nibret… - Infection and Drug …, 2023 - Taylor & Francis
Introduction Drug resistance (DR) in Mycobacterium tuberculosis complex (MTBC) is mainly
associated with certain lineages and varies across regions and countries. The Beijing …

Patterns and profiles of drug resistance-conferring mutations in Mycobacterium tuberculosis genotypes isolated from tuberculosis-suspected attendees of spiritual …

MA Reta, NE Maningi, PB Fourie - Frontiers in Public Health, 2024 - frontiersin.org
Purpose This study examined the patterns and frequency of genetic changes responsible for
resistance to first-line (rifampicin and isoniazid), fluoroquinolones, and second-line …

[HTML][HTML] Genetic diversity of Mycobacterium tuberculosis strains isolated from spiritual holy water site attendees in Northwest Ethiopia. A cross-sectional study

MA Reta, HM Said, NE Maningi, GY Wubetu… - New Microbes and New …, 2024 - Elsevier
Background The genetic diversity of Mycobacterium tuberculosis complex (MTBC) strains
was characterized among isolates from individuals with pulmonary tuberculosis (PTB) …

Molecular epidemiology of tuberculosis in the Somali region, eastern Ethiopia

G Worku, B Gumi, B Mohammedbirhan, M Girma… - Frontiers in …, 2022 - frontiersin.org
Background Tuberculosis (TB) is one of the leading causes of morbidity and mortality in low-
income countries like Ethiopia. However, because of the limited laboratory infrastructure …

Phenotypic and genotypic drug susceptibility patterns of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Central and Southern Ethiopia

M Tilahun, T Wegayehu, B Wondale, TT Gebresilase… - Plos one, 2023 - journals.plos.org
Introduction The persistence of tuberculosis (TB) infection in some patients after treatment
has highlighted the importance of drug susceptibility testing (DST). This study aimed to …

Whole-genome sequencing-based genetic diversity, transmission dynamics, and drug-resistant mutations in Mycobacterium tuberculosis isolated from …

B Chekesa, H Singh, N Gonzalez-Juarbe… - Frontiers in Public …, 2024 - frontiersin.org
Background Extrapulmonary tuberculosis (EPTB) refers to a form of Tuberculosis (TB) where
the infection occurs outside the lungs. Despite EPTB being a devastating disease of public …

Spiritual Holy Water Sites in Ethiopia: Unrecognized High‐Risk Settings for Transmission of Pulmonary Tuberculosis

MA Reta, NE Maningi, GY Wubetu… - International Journal …, 2024 - Wiley Online Library
Ethiopia is a high‐tuberculosis (TB) burden country with 157 new cases per 100,000 people,
with 23,800 TB‐related deaths in 2020. In Ethiopia, TB patients have different healthcare …