Chromatin lysine acylation: On the path to chromatin homeostasis and genome integrity

F Chen, X He, W Xu, L Zhou, Q Liu, W Chen… - Cancer …, 2024 - Wiley Online Library
The fundamental role of cells in safeguarding the genome's integrity against DNA double‐
strand breaks (DSBs) is crucial for maintaining chromatin homeostasis and the overall …

[HTML][HTML] Improved Mass Spectrometry-based methods reveal abundant propionylation and tissue specific histone propionylation profiles

A Vai, R Noberini, C Ghirardi, DR de Paula… - Molecular & Cellular …, 2024 - Elsevier
Histone post-translational modifications (PTMs) have crucial roles in a multitude of cellular
processes, and their aberrant levels have been linked with numerous diseases, including …

Proteome Analysis Related to Unsaturated Fatty Acid Synthesis by Interfering with Bovine Adipocyte ACSL1 Gene

Y Bai, J Li, Y Wei, Z Chen, Z Liu, D Guo, X Jia, Y Niu… - Antioxidants, 2024 - mdpi.com
Unsaturated fa y acids (UFAs) in beef play a vital role in promoting human health. Longchain
fa y acyl-CoA synthase 1 (ACSL1) is a crucial gene for UFA synthesis in bovine adipocytes …

[HTML][HTML] A circular engineered sortase for interrogating histone H3 in chromatin

SD Whedon, K Lee, ZA Wang, E Zahn, C Lu… - …, 2024 - pmc.ncbi.nlm.nih.gov
Reversible modification of the histone H3 N-terminal tail is critical in regulating chromatin
structure, gene expression, and cell states, while its dysregulation contributes to disease …