Revealing neuronal function through microelectrode array recordings

MEJ Obien, K Deligkaris, T Bullmann… - Frontiers in …, 2015 - frontiersin.org
Microelectrode arrays and microprobes have been widely utilized to measure neuronal
activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate …

State-of-the-art MEMS and microsystem tools for brain research

JP Seymour, F Wu, KD Wise, E Yoon - Microsystems & …, 2017 - nature.com
Mapping brain activity has received growing worldwide interest because it is expected to
improve disease treatment and allow for the development of important neuromorphic …

Functional neuronal circuitry and oscillatory dynamics in human brain organoids

T Sharf, T Van Der Molen, SMK Glasauer… - Nature …, 2022 - nature.com
Human brain organoids replicate much of the cellular diversity and developmental anatomy
of the human brain. However, the physiology of neuronal circuits within organoids remains …

SpikeInterface, a unified framework for spike sorting

AP Buccino, CL Hurwitz, S Garcia, J Magland… - Elife, 2020 - elifesciences.org
Much development has been directed toward improving the performance and automation of
spike sorting. This continuous development, while essential, has contributed to an over …

An electronic neuromorphic system for real-time detection of high frequency oscillations (HFO) in intracranial EEG

M Sharifshazileh, K Burelo, J Sarnthein… - Nature …, 2021 - nature.com
The analysis of biomedical signals for clinical studies and therapeutic applications can
benefit from embedded devices that can process these signals locally and in real-time. An …

In Vitro Multi-Functional Microelectrode Array Featuring 59 760 Electrodes, 2048 Electrophysiology Channels, Stimulation, Impedance Measurement, and …

J Dragas, V Viswam, A Shadmani… - IEEE journal of solid …, 2017 - ieeexplore.ieee.org
Biological cells are characterized by highly complex phenomena and processes that are, to
a great extent, interdependent. To gain detailed insights, devices designed to study cellular …

CMOS electrochemical pH localizer-imager

HS Jung, WB Jung, J Wang, J Abbott, A Horgan… - Science …, 2022 - science.org
pH controls a large repertoire of chemical and biochemical processes in water. Densely
arrayed pH microenvironments would parallelize these processes, enabling their high …

Optimal electrode size for multi-scale extracellular-potential recording from neuronal assemblies

V Viswam, MEJ Obien, F Franke, U Frey… - Frontiers in …, 2019 - frontiersin.org
Advances in microfabrication technology have enabled the production of devices containing
arrays of thousands of closely spaced recording electrodes, which afford subcellular …

A very large-scale microelectrode array for cellular-resolution electrophysiology

D Tsai, D Sawyer, A Bradd, R Yuste… - Nature …, 2017 - nature.com
In traditional electrophysiology, spatially inefficient electronics and the need for tissue-to-
electrode proximity defy non-invasive interfaces at scales of more than a thousand low …

Intracellular recording of cardiomyocyte action potentials with nanopatterned volcano-shaped microelectrode arrays

BXE Desbiolles, E De Coulon, A Bertsch, S Rohr… - Nano …, 2019 - ACS Publications
Micronanotechnology-based multielectrode arrays have led to remarkable progress in the
field of transmembrane voltage recording of excitable cells. However, providing long-term …