Synthesis and clinical application of new drugs approved by FDA in 2022

JY Zhang, YT Wang, L Sun, SQ Wang, ZS Chen - Molecular Biomedicine, 2023 - Springer
The pharmaceutical industry had a glorious year in 2022, with a total of 37 new drugs
including 20 new chemical entities (NCEs) and 17 new biological entities (NBEs) approved …

[HTML][HTML] A Comprehensive Systematic Review of the Latest Management Strategies for Hepatorenal Syndrome: A Complicated Syndrome to Tackle

P Roy, N Minhaz, P Shah-Riar, SY Simona, T Tasha… - Cureus, 2023 - ncbi.nlm.nih.gov
Hepatorenal syndrome (HRS), defined by the extreme manifestation of renal impairment in
patients with cirrhosis, is characterized by reduced renal blood flow and glomerular filtration …

Machine learning-based prediction model of acute kidney injury in patients with acute respiratory distress syndrome

S Wei, Y Zhang, H Dong, Y Chen, X Wang, X Zhu… - BMC Pulmonary …, 2023 - Springer
Background Acute kidney injury (AKI) can make cases of acute respiratory distress
syndrome (ARDS) more complex, and the combination of the two can significantly worsen …

[HTML][HTML] Hepatitis virus C-associated nephropathy: a review and update

E Habas Sr, KL Farfar, N Errayes, AM Habas… - Cureus, 2022 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection causes hepatic and extrahepatic organ involvement.
Chronic kidney disease (CKD) is a prevalent non-communicable disorder, accounting for …

Formation of a Disulfide Bridge on the Resin during Solid-Phase Synthesis of Terlipressin: Influence of the Boc-Protected and Free N-Terminal Amino Group

D Avdeev, MV Ovchinnikov… - … Process Research & …, 2023 - ACS Publications
An industry-ready approach for the synthesis of terlipressin is developed: the entire peptide
chain assembly and subsequent disulfide bond closure are carried out on a polymeric …

肝硬化并发肝肾综合征患者血清细胞因子和外周血淋巴细胞亚群变化及短期预后分析

常凯, 黄亚秋, 于立丽, 熊建新, 杨明 - 实用肝脏病杂志, 2023 - manu43.magtech.com.cn
肝硬化并发肝肾综合征患者血清细胞因子和外周血淋巴细胞亚群变化及短期预后分析∗ Page 1
∗ 基金项目:海南省医药卫生科研项目(编号:20A200083) 作者单位:572299 海南省五指山市海南 …

[HTML][HTML] 失代偿性肝硬化合并肾损伤的最新分型与HRS 的诊治进展

周炜, 李素华 - Advances in Clinical Medicine, 2023 - hanspub.org
由于失代偿性肝硬化患者特殊的病理生理状况, 他们更容易出现肾脏损伤, 从而影响其生活质量.
类型包括急性肾损伤, 急性肾脏病, 慢性肾脏病, 还包含了一种特殊的急性肾损伤, 即肝肾综合征 …

A Risk-Prediction Model for Hepatorenal Syndrome in Patients with Liver Failure: A Retrospective Analysis

HAO LIU, LAN Yanmei, R ZHANG, K ZHANG, M Wang… - 2024 - researchsquare.com
Objectives To identify the risk factors and develop a risk-prediction model for hepatorenal
syndrome (HRS) in patients with liver failure (LF). Methods A retrospective case-control …

Hepatitis Virus C-associated Nephropathy: A Review and Update

H Elmukhtar Sr, KL Farfar, E Nada, AM Habas… - Cureus, 2022 - search.proquest.com
Hepatitis C virus (HCV) infection causes hepatic and extrahepatic organ involvement.
Chronic kidney disease (CKD) is a prevalent non-communicable disorder, accounting for …

[HTML][HTML] A Comparative Analysis of Norepinephrine with Midodrine/Octreotide in Patients with Hepatorenal Syndrome-acute Kidney Injury

M Maghsudlou, A Nourozi… - The Open …, 2024 - openurologyandnephrologyjournal …
Background Hepatorenal Syndrome (HRS) is a severe complication of end-stage liver
disease characterized by functional renal impairment. This study aimed to assess the …