This review article will consider the preparation and application of ynones in synthetic
organic chemistry. Concerning the preparation of these bifunctional compounds, several …

Nitrogen-containing π-excessive aromatic heterocycles, in particular, carbazoles,
indolocarbazoles, benzocarbazoles, and carbolines have been considered the fundamental …

Spirocyclic indole derivatives are fascinating tridimensional molecular scaffolds from both a
synthetic and a biological point of view. Among the many strategies developed to access …

Indole-tethered ynones form an intramolecular electron donor–acceptor complex that can
undergo visible-light-induced charge transfer to promote thiyl radical generation from thiols …

Indole-ynones have been established as general substrates for radical dearomatizing
spirocyclization cascade reactions. Five distinct and varied synthetic protocols have been …

Ag (I)-catalyzed highly diastereoselective construction of divergent spiroindolines is
disclosed herein. The approach proceeds via dearomatizing spirocyclization of indole …

A one-pot protocol for the dearomatizing spirocyclization/cross-coupling of alkyne-tethered
indoles/pyrroles is described. Mechanistic studies support a process by which palladium …

Indoles are amongst the most important classes of heteroaromatics in organic chemistry,
commonly found in biologically active natural products and therapeutically useful …

A palladium-catalyzed dearomatization of indoles with alkynes has been developed,
providing an efficient route to access a variety of synthetically useful …

An operationally simple, high yielding three-step cascade process is described for the direct
conversion of indole-tethered ynones into functionalized quinolines. A single “multitasking” …