The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

Homologous recombination (HR) is an important mechanism for the repair of damaged
chromosomes, for preventing the demise of damaged replication forks, and for several other …

INTRODUCTION Diversity in the sequence of the human genome, arising from
recombinations and mutations, is fundamental to human evolution and human diversity …

We present an analysis of over 1,100 of the∼ 10,000 predicted proteins encoded by the
genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of …

Accurate segregation of homologous chromosomes during meiosis depends on the ability of
meiotic cells to promote reciprocal exchanges between parental DNA strands, known as …

Demethylation by the AlkB dioxygenases represents an important mechanism for repair of N-
alkylated nucleotides. However, little is known about their functions in mammalian cells. We …

In Saccharomyces cerevisiae the MSH4-MSH5, MLH1-MLH3, and MUS81-MMS4
complexes act to promote crossing over during meiosis. MSH4-MSH5, but not MUS81 …

Gene conversions resulting from meiotic recombination are critical in shaping genome
diversification and evolution. How the extent of gene conversions is regulated is unknown …

Mutations in the human ChlR1 gene are associated with a unique genetic disorder known
as Warsaw breakage syndrome characterized by cellular defects in sister chromatid …

Recent studies in Saccharomyces cerevisiae have unveiled that meiotic recombination
crossovers are formed by two genetically distinct pathways: a major interference‐sensitive …