Introduction The aim of the present review is to track the evolution of wearable IMUs from
their use in supervised laboratory-and ambulatory-based settings to their application for long …

Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a
pressing need for tools to facilitate remote visits and monitoring. Digital health technology …

Introduction Existing mobility endpoints based on functional performance, physical
assessments and patient self-reporting are often affected by lack of sensitivity, limiting their …

Physical mobility is essential to health, and patients often rate it as a high-priority clinical
outcome. Digital mobility outcomes (DMOs), such as real-world gait speed or step count …

With disease-modifying drugs on the horizon for degenerative ataxias, ecologically valid,
finely granulated, digital health measures are highly warranted to augment clinical and …

Background Although digital mobility outcomes (DMOs) can be readily calculated from real-
world data collected with wearable devices and ad-hoc algorithms, technical validation is …

Introduction: Accurately assessing people's gait, especially in real-world conditions and in
case of impaired mobility, is still a challenge due to intrinsic and extrinsic factors resulting in …

Background The development of optimal strategies to treat impaired mobility related to
ageing and chronic disease requires better ways to detect and measure it. Digital health …

Background Clinical and regulatory acceptance of upcoming molecular treatments in
degenerative ataxias might greatly benefit from ecologically valid endpoints that capture …

Wearable devices are used in movement analysis and physical activity research to extract
clinically relevant information about an individual's mobility. Still, heterogeneity in protocols …