Accumulating evidence suggests that a high tumour burden has a negative effect on
anticancer immunity. The concept of tumour burden, simply defined as the total amount of …

It is long recognized that cancer cells display increased glucose uptake and metabolism. In
a rate-limiting step for glucose metabolism, the glucose transporter (GLUT) proteins facilitate …

Purpose: Ketogenic diets are high in fat and low in carbohydrates as well as protein which
forces cells to rely on lipid oxidation and mitochondrial respiration rather than glycolysis for …

Adenocarcinoma (ADC) and squamous cell carcinoma (SqCC) are the two predominant
subtypes of non-small cell lung cancer (NSCLC) and are distinct in their histological …

The diagnostic definition of indeterminate lung nodules as malignant or benign poses a
major challenge for clinicians. We discovered a potential marker, the sodium-dependent …

It is hoped that in the not too distant future, noninvasive imaging–based molecular
interrogation and characterization of tumors can improve our fundamental understanding of …

Inhibition of glycolysis has been considered as a therapeutic approach in aggressive
cancers including lung cancer. Abbreviated gluconeogenesis, mediated by …

The Society of Nuclear Medicine and Molecular Imaging has defined molecular imaging as
“the visualization, characterization, and measurement of biological processes at the …

Introduction Biological features of non–small-cell lung carcinomas (NSCLCs) are important
determinants for prognosis. In this study, differences in glucose metabolism between adeno …

Purpose The study aims to investigate the correlations between positron emission
tomography (PET) texture features, X-ray computed tomography (CT) texture features, and …