Aerobic glycolysis, also referred to as the Warburg effect, has been regarded as the
dominant metabolic phenotype in cancer cells for a long time. More recently, it has been …

Mitochondrial complex V (CV) generates cellular energy as adenosine triphosphate (ATP).
Mitochondrial disease caused by the m. 8993T> G pathogenic variant in the CV subunit …

Transmitochondrial cybrids and multiple OMICs approaches were used to understand
mitochondrial reprogramming and mitochondria-regulated cancer pathways in triple …

Extensively revised, the fourth edition of this highly successful book takes into account the
many newly determined protein structures that provide molecular insight into chemiosmotic …

Human mitochondria produce ATP and metabolites to support development and maintain
cellular homeostasis. Mitochondria harbor multiple copies of a maternally inherited, non …

Background Mitochondrial dysfunction is involved in several diseases ranging from genetic
mitochondrial disorders to chronic metabolic diseases. An emerging approach to potentially …

Blindness poses a growing global challenge, with approximately 26% of cases attributed to
degenerative retinal diseases. While gene therapy, optogenetic tools, photosensitive …

Mitochondrial-nucleus cross talks and mitochondrial retrograde regulation can play a
significant role in cellular properties. Transmitochondrial cybrid systems (cybrids) are an …

Mitochondria are semi-autonomous organelles that play essential roles in cellular
metabolism and programmed cell death pathways. Genomic, functional and structural …

Aging is characterized by a progressive decline in organism functions due to the impairment
of all organs. The deterioration of both proliferative tissues in liver, skin and the vascular …