Proteomics can be viewed as an experimental approach to explain the information
contained in genomic sequences in terms of the structure, function, and control of biological …

Profound changes are occurring in the strategies that biotechnology-based industries are
deploying in the search for exploitable biology and to discover new products and develop …

A mass spectrometry-based method is described for simultaneous identification and
quantitation of individual proteins and for determining changes in the levels of modifications …

Der" Sewald/Jakubke" ist und bleibt das einzige moderne, auf dem neuesten
wissenschaftlichen Stand gehaltene fortgeschrittene Lehrbuch der Peptid-Biochemie! Auch …

Identifying sites of post-translational modifications on proteins is a major challenge in
proteomics. O-Linked β-N-acetylglucosamine (O-GlcNAc) is a dynamic nucleocytoplasmic …

This paper describes a prototype of an integrated fluorescence detection system that uses a
microavalanche photodiode (μAPD) as the photodetector for microfluidic devices fabricated …

We describe and demonstrate a global strategy that extends the sensitivity, dynamic range,
comprehensiveness, and throughput of proteomic measurements based upon the use of …

This laboratory guide for successful electrophoretic separations is divided into two parts to
provide readers with a thorough presentation of the fundamentals followed by a detailed …

A MALDI QqTOF mass spectrometer has been used to identify proteins separated by one-
dimensional or two-dimensional gel electrophoresis at the femtomole level. The high mass …

A comprehensive on-line two-dimensional 2D-HPLC system with integrated sample
preparation was developed for the analysis of proteins and peptides with a molecular weight …