Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic
G Ranieri, R Patruno, E Ruggieri… - Current medicinal …, 2006 - ingentaconnect.com
Angiogenesis is important in the growth and progression of solid tumours. The main pro-
angiogenic factor, namely vascular endothelial growth factor (VEGF), also known as …
angiogenic factor, namely vascular endothelial growth factor (VEGF), also known as …
Biomarkers in cervical cancer screening
N Wentzensen, M von Knebel Doeberitz - Disease markers, 2007 - content.iospress.com
In industrialized countries, population wide cytological screening programs using the Pap
test have led to a substantial reduction of the incidence of cervical cancer. Despite this …
test have led to a substantial reduction of the incidence of cervical cancer. Despite this …
Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1α protein accumulation and vascular endothelial growth factor …
X Tang, Q Zhang, J Nishitani, J Brown, S Shi… - Clinical Cancer Research, 2007 - AACR
Abstract Purpose: Human papillomavirus (HPV)-16 oncoproteins, E6 and E7, are associated
with enhanced tumor angiogenesis in human cervical cancers. The purpose of this study …
with enhanced tumor angiogenesis in human cervical cancers. The purpose of this study …
Macrophages, inflammation and risk of cervical intraepithelial neoplasia (CIN) progression—clinicopathological correlation
LS Hammes, RR Tekmal, P Naud, MI Edelweiss… - Gynecologic …, 2007 - Elsevier
OBJECTIVE.: To evaluate the population of macrophages during the cervical malignant
transformation and its influence in CIN outcome. METHODS.: Biopsies from 26 normal …
transformation and its influence in CIN outcome. METHODS.: Biopsies from 26 normal …
Incident cervical HPV infections in young women: transition probabilities for CIN and infection clearance
RP Insinga, G Perez, CM Wheeler, LA Koutsky… - … Biomarkers & Prevention, 2011 - AACR
Background: We describe transition probabilities for incident human papillomavirus (HPV)
16/18/31/33/35/45/52/58/59 infections and cervical intraepithelial neoplasia (CIN) 1 lesions …
16/18/31/33/35/45/52/58/59 infections and cervical intraepithelial neoplasia (CIN) 1 lesions …
Increased expression of RRM2 by human papillomavirus E7 oncoprotein promotes angiogenesis in cervical cancer
Background: The purpose of this study was to confirm that RRM2 as a novel target of HPVE7
involved in cervical cancer angiogenesis. Methods: Gene expression was analysed by RT …
involved in cervical cancer angiogenesis. Methods: Gene expression was analysed by RT …
Exploring the correlation between progression of human papillomavirus infection towards carcinogenesis and nutrition
A Letafati, T Sakhavarz, MM Khosravinia… - Microbial …, 2023 - Elsevier
Human papillomavirus (HPV) is a common sexually transmitted infection that can lead to the
development of various types of cancer. While there are vaccines available to prevent HPV …
development of various types of cancer. While there are vaccines available to prevent HPV …
Molecular targets of HPV oncoproteins: potential biomarkers for cervical carcinogenesis
AC de Freitas, EC Coimbra, MCG Leitão - Biochimica et Biophysica Acta …, 2014 - Elsevier
Cervical cancer is the second most common cancer among women worldwide and is
responsible for 275,000 deaths each year. Persistent infection with high-risk human …
responsible for 275,000 deaths each year. Persistent infection with high-risk human …
[HTML][HTML] Hypoxia-inducible factor 1 and its role in viral carcinogenesis
The advent of modern molecular biology has allowed for the discovery of several
mechanisms by which oncoviruses promote carcinogenesis. Remarkably, nearly all human …
mechanisms by which oncoviruses promote carcinogenesis. Remarkably, nearly all human …
Mechanisms of crosstalk between the oropharyngeal microbiome and human papillomavirus in oropharyngeal carcinogenesis: a mini review
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
globally. Notably, human papillomavirus (HPV)-positive oropharyngeal squamous cell …
globally. Notably, human papillomavirus (HPV)-positive oropharyngeal squamous cell …