Myocardial injury induces significant changes in ventricular structure and function at both the
cellular and anatomic level, leading to ventricular remodeling and subsequent heart failure …

For almost 30 years, urgent revascularization termed primary percutaneous coronary
intervention has been a cornerstone of modern care for acute myocardial infarction (AMI). It …

Background: Acute myocardial infarction remains a leading cause of chronic heart failure.
Excessive myocardial oxygen demand relative to supply is the fundamental mechanism of …

Acute myocardial infarction (AMI) is associated with high morbidity and mortality worldwide.
Although early reperfusion is the most effective strategy to salvage ischemic myocardium …

Background Reducing myocardial damage is a prerequisite to prevent chronic heart failure
after acute myocardial infarction (AMI). Although vagal nerve stimulation (VNS) has been …

Background Post-myocardial infarction ventricular septal defect (PIVSD) is a complication of
acute myocardial infarction with high mortality. A percutaneous left ventricular assist device …

Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality.
Pioneering preclinical work reported by Peter Maroko and Eugene Braunwald in 1971 …

In recent years, development of mechanical circulatory support devices has proved to be a
new treatment modality, in addition to standard pharmacological therapy, for patients with …

Post-myocardial infarction ventricular septal rupture (PIVSR) is becoming increasingly rare
in the percutaneous coronary intervention era; however, the mortality rates remain high …

The oxygen supply-demand imbalance is the fundamental pathophysiology of myocardial
infarction (MI). Reducing myocardial oxygen consumption (MVO 2) in acute MI (AMI) …