New principles for glycoside‐bond formation

X Zhu, RR Schmidt - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Meeting the demand for sugars: The importance of oligosaccharides and glycoconjugates in
biological systems has stimulated a need to access significant amounts of these …

Effect of N-linked glycosylation on glycopeptide and glycoprotein structure

B Imperiali, SE O'Connor - Current opinion in chemical biology, 1999 - Elsevier
Asparagine-linked glycosylation is an enzyme-catalyzed, co-translational protein
modification reaction that has the capacity to influence either the protein folding process or …

Solid-phase oligosaccharide synthesis and combinatorial carbohydrate libraries

PH Seeberger, WC Haase - Chemical reviews, 2000 - ACS Publications
The transfer of information is a fundamental process of life and central to all cellular systems.
From a biological perspective, information needs to be transmitted intracellularly and …

Toward automated synthesis of oligosaccharides and glycoproteins

P Sears, CH Wong - Science, 2001 - science.org
The discovery of previously unknown functions associated with carbohydrates and the study
of their structure-function relations are of current interest in carbohydrate chemistry and …

[图书][B] Carbohydrate-based drug discovery, 2 volume set

CH Wong - 2003 - books.google.com
Die Suche nach Medikamenten mit neuen oder verbesserten Eigenschaften hat das
Interesse am pharmazeutischen Potenzial von Kohlenhydraten enorm verstärkt. Dies gilt …

Linkers for solid phase organic synthesis

IW James - Tetrahedron, 1999 - Elsevier
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Carbohydrates as the next frontier in pharmaceutical research

DB Werz, PH Seeberger - Chemistry–A European Journal, 2005 - Wiley Online Library
Synthetic carbohydrates and glycoconjugates are used to study their roles in biological
important processes such as inflammation, cell–cell recognition, immunological response …

Mechanistic studies and methods to prevent aglycon transfer of thioglycosides

Z Li, JC Gildersleeve - Journal of the American Chemical Society, 2006 - ACS Publications
Thioglycosides have been employed extensively for the synthesis of complex
oligosaccharides, carbohydrate libraries, and mimetics of O-glycosides. While very useful …

Neue Prinzipien für die Bildung von glycosidischen Bindungen

X Zhu, RR Schmidt - Angewandte Chemie, 2009 - Wiley Online Library
Abstract Die wichtige Rolle, die Oligosaccharide und Glycokonjugate in biologischen
Systemen spielen, erfordert immer neue und vor allem größere Mengen dieser Moleküle …

Toward solution-phase automated iterative synthesis: fluorous-tag assisted solution-phase synthesis of linear and branched mannose oligomers

FA Jaipuri, NL Pohl - Organic & biomolecular chemistry, 2008 - pubs.rsc.org
We report herein the first synthesis of linear and branched mannose oligosaccharides using
fluorous-tag assistance with reagents and FSPE protocols that are amenable to automation …