Food polyphenols and type II diabetes mellitus: pharmacology and mechanisms

R Naz, F Saqib, S Awadallah, M Wahid, MF Latif, I Iqbal… - Molecules, 2023 - mdpi.com
Type II diabetes mellitus and its related complications are growing public health problems.
Many natural products present in our diet, including polyphenols, can be used in treating …

Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk

JM Sanches, LN Zhao, A Salehi, CB Wollheim… - The FEBS …, 2023 - Wiley Online Library
Diabetes is a complex and multifactorial disease that affects millions of people worldwide,
reducing the quality of life significantly, and results in grave consequences for our health …

A high-fat diet increases gut microbiota biodiversity and energy expenditure due to nutrient difference

B Wang, Q Kong, X Li, J Zhao, H Zhang, W Chen… - Nutrients, 2020 - mdpi.com
A high-fat diet (HFD) can easily induce obesity and change the gut microbiota and its
metabolites. However, studies on the effects of high-fat diets on the host have drawn …

Bacteroides acidifaciens in the gut plays a protective role against CD95-mediated liver injury

H Wang, Q Wang, C Yang, M Guo, X Cui, Z Jing… - Gut …, 2022 - Taylor & Francis
The intestinal flora plays an important role in the development of many human and animal
diseases. Microbiome association studies revealed the potential regulatory function of …

[HTML][HTML] Escherichia fergusonii promotes nonobese nonalcoholic fatty liver disease by interfering with host hepatic lipid metabolism through its own msRNA 23487

FZ Xin, ZH Zhao, XL Liu, Q Pan, ZX Wang… - Cellular and molecular …, 2022 - Elsevier
Background & Aims Gut microbiota and microbial factors regulate the pathogenesis of
nonalcoholic fatty liver disease (NAFLD) in patients with obesity and metabolic …

Nonalcoholic fatty liver disease (NAFLD) as model of gut–liver axis interaction: from pathophysiology to potential target of treatment for personalized therapy

F Fianchi, A Liguori, A Gasbarrini, A Grieco… - International journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of liver disease worldwide,
affecting both adults and children and will result, in the near future, as the leading cause of …

Noni (Morinda citrifolia L.) fruit phenolic extract supplementation ameliorates NAFLD by modulating insulin resistance, oxidative stress, inflammation, liver metabolism …

R Wang, L Wang, H Wu, L Zhang, X Hu, C Li… - Food Research …, 2022 - Elsevier
The liver-protective activity of phenolics has been consistently reported, but the underlying
protective mechanism of phenolic extract from noni fruit (NFE) against high-fat-diet (HFD) …

[HTML][HTML] Aryl hydrocarbon receptor deficiency in intestinal epithelial cells aggravates alcohol-related liver disease

M Qian, J Liu, D Zhao, P Cai, C Pan, W Jia… - Cellular and molecular …, 2022 - Elsevier
Background & Aims The ligand-activated transcription factor, aryl hydrocarbon receptor
(AHR) can sense xenobiotics, dietary, microbial, and metabolic cues. Roles of Ahr in …

[HTML][HTML] Prebiotic properties of Ganoderma lucidum polysaccharides with special enrichment of Bacteroides ovatus and B. uniformis in vitro

L Yang, X Kang, W Dong, L Wang, S Liu… - Journal of Functional …, 2022 - Elsevier
Polysaccharide is the major biologically active constituent in functional mushroom
Ganoderma lucidum. This study was aim to investigate the utilizability of G. lucidum …

Gut microbiome and metabolome response of Pu-erh tea on metabolism disorder induced by chronic alcohol consumption

Y Liu, Y Luo, X Wang, L Luo, K Sun… - Journal of agricultural …, 2020 - ACS Publications
This study investigated the protective effects of pu-erh tea extract (PTE) on alcohol-induced
microbiomic and metabolomic disorders. In chronic alcohol-exposed mice, PTE ameliorated …