Computational modeling and engineering in pediatric and congenital heart disease

AL Marsden, JA Feinstein - Current opinion in pediatrics, 2015 - journals.lww.com
Computational modeling is emerging as a crucial tool for clinical decision-making and
evaluation of novel surgical methods and interventions in pediatric cardiology and beyond …

Effects of uncertainty of outlet boundary conditions in a patient-specific case of aortic coarctation

MN Antonuccio, A Mariotti, BM Fanni… - Annals of biomedical …, 2021 - Springer
Abstract Computational Fluid Dynamics (CFD) simulations of blood flow are widely used to
compute a variety of hemodynamic indicators such as velocity, time-varying wall shear …

A methodological paradigm for patient‐specific multi‐scale CFD simulations: from clinical measurements to parameter estimates for individual analysis

S Pant, B Fabrèges, JF Gerbeau… - … journal for numerical …, 2014 - Wiley Online Library
SUMMARY A new framework for estimation of lumped (for instance, Windkessel) model
parameters from uncertain clinical measurements is presented. The ultimate aim is to …

A flexible framework for sequential estimation of model parameters in computational hemodynamics

CJ Arthurs, N Xiao, P Moireau, T Schaeffter… - Advanced modeling and …, 2020 - Springer
A major challenge in constructing three dimensional patient specific hemodynamic models
is the calibration of model parameters to match patient data on flow, pressure, wall motion …

Inverse problems in reduced order models of cardiovascular haemodynamics: aspects of data assimilation and heart rate variability

S Pant, C Corsini, C Baker, TY Hsia… - Journal of The …, 2017 - royalsocietypublishing.org
Inverse problems in cardiovascular modelling have become increasingly important to
assess each patient individually. These problems entail estimation of patient-specific model …

A physiologically realistic virtual patient database for the study of arterial haemodynamics

G Jones, J Parr, P Nithiarasu… - International Journal for …, 2021 - Wiley Online Library
This study creates a physiologically realistic virtual patient database (VPD), representing the
human arterial system, for the primary purpose of studying the effects of arterial disease on …

A parameter estimation framework for patient-specific hemodynamic computations

L Itu, P Sharma, T Passerini, A Kamen, C Suciu… - Journal of …, 2015 - Elsevier
We propose a fully automated parameter estimation framework for performing patient-
specific hemodynamic computations in arterial models. To determine the personalized …

Modified Navier–Stokes equations for the outflow boundary conditions in hemodynamics

G Arbia, IE Vignon-Clementel, TY Hsia… - European Journal of …, 2016 - Elsevier
We present a new approach for the outflow boundary conditions of Navier–Stokes equations
in hemodynamics. We first describe some existing 3D–0D coupling methods and highlight …

[HTML][HTML] Numerical simulation of aortic coarctations of different grades of severity: Flow features and importance of outlet boundary conditions

A Mariotti, MN Antonuccio, M Morello, MV Salvetti… - Computers & …, 2023 - Elsevier
Numerical simulations of the blood flow inside a patient-specific thoracic aorta in presence
of coarctation are considered. Different grades of severity of the coarctation are obtained by …

Pulmonary hemodynamics simulations before stage 2 single ventricle surgery: patient-specific parameter identification and clinical data assessment

G Arbia, C Corsini, C Baker, G Pennati, TY Hsia… - Cardiovascular …, 2015 - Springer
Single ventricle heart defects involve pathologies in which the heart has only one functional
pumping chamber. In these conditions, treatment consists of three staged procedures. At …