Individual proteins and protein complexes undergo various motion types, including free
diffusion, confinement, subdiffusion and directed motion. Different motion behaviours reflect …

Visualizing the structure and dynamics of biomolecules is critical to understand biological
function, and requires methods to fluorescently label targets of interest in their cellular …

In this study, a neoteric self-enhanced nanocomposite boron carbon nitride nanosheets
(BCN NSs)-Ru obtained by chemical crosslinking between boron carbon nitride nanosheets …

Reaching sub-millisecond 3D tracking of individual molecules in living cells would enable
direct measurements of diffusion-limited macromolecular interactions under physiological …

The ribosome serves as the universally conserved translator of the genetic code into
proteins and supports life across diverse temperatures ranging from below freezing to above …

Single-particle tracking microscopy is a powerful technique to investigate how proteins
dynamically interact with their environment in live cells. However, the analysis of tracks is …

Experimental observations tracing back to the 1960s imply that ribosome quantities play a
prominent role in determining a cell's growth. Nevertheless, in biologically relevant …

Messenger RNA (mRNA) vaccines against infectious diseases and for anticancer
immunotherapy have garnered considerable attention. Currently, mRNA vaccines …

It is known that mRNAs and the machinery that translates them are not uniformly distributed
throughout the cytoplasm. As a result, the expression of some genes is localized to particular …

Mechanistic details of the signal recognition particle (SRP)-mediated insertion of membrane
proteins have been described from decades of in vitro biochemical studies. However, the …