Mitochondrial transfer and regulators of mesenchymal stromal cell function and therapeutic efficacy

A Mohammadalipour, SP Dumbali… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the surrounding
microenvironment in both normal physiology and pathological conditions. While MSCs …

The functions, methods, and mobility of mitochondrial transfer between cells

Y Qin, X Jiang, Q Yang, J Zhao, Q Zhou… - Frontiers in oncology, 2021 - frontiersin.org
Mitochondria are vital organelles in cells, regulating energy metabolism and apoptosis.
Mitochondrial transcellular transfer plays a crucial role during physiological and pathological …

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

X Wang, HH Gerdes - Cell Death & Differentiation, 2015 - nature.com
Tunneling nanotubes (TNTs) are F-actin-based membrane tubes that form between cells in
culture and in tissues. They mediate intercellular communication ranging from electrical …

Cell connections by tunneling nanotubes: effects of mitochondrial trafficking on target cell metabolism, homeostasis, and response to therapy

ML Vignais, A Caicedo, JM Brondello… - Stem cells …, 2017 - Wiley Online Library
Intercellular communications play a major role in tissue homeostasis and responses to
external cues. Novel structures for this communication have recently been described. These …

Tunneling nanotubes: Diversity in morphology and structure

MW Austefjord, HH Gerdes, X Wang - Communicative & integrative …, 2014 - Taylor & Francis
Tunneling nanotubes (TNTs) are recently discovered thin membranous tubes that
interconnect cells. During the last decade, research has shown TNTs to be diverse in …

Tunneling nanotubes and tumor microtubes in cancer

C Roehlecke, MHH Schmidt - Cancers, 2020 - mdpi.com
Intercellular communication among cancer cells and their microenvironment is crucial to
disease progression. The mechanisms by which communication occurs between distant …

Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes

E Delage, DC Cervantes, E Pénard, C Schmitt… - Scientific reports, 2016 - nature.com
Abstract Tunneling Nanotubes (TNTs) are actin enriched filopodia-like protrusions that play
a pivotal role in long-range intercellular communication. Different pathogens use TNT-like …

Specialized intercellular communications via cytonemes and nanotubes

YM Yamashita, M Inaba… - Annual review of cell and …, 2018 - annualreviews.org
In recent years, thin membrane protrusions such as cytonemes and tunneling nanotubes
have emerged as a novel mechanism of intercellular communication. Protrusion-based …

Bridging the gap: virus long-distance spread via tunneling nanotubes

RJJ Jansens, A Tishchenko, HW Favoreel - Journal of virology, 2020 - Am Soc Microbiol
Tunneling nanotubes (TNTs) are actin-based intercellular conduits that connect distant cells
and allow intercellular transfer of molecular information, including genetic information …

Tunneling nanotubes and related structures: molecular mechanisms of formation and function

S Dagar, D Pathak, HV Oza… - Biochemical …, 2021 - portlandpress.com
Tunneling nanotubes (TNTs) are F-actin-based, membrane-enclosed tubular connections
between animal cells that transport a variety of cellular cargo. Over the last 15 years since …