A harmonized public resource of deeply sequenced diverse human genomes

Z Koenig, MT Yohannes, LL Nkambule… - Genome …, 2024 - genome.cshlp.org
Underrepresented populations are often excluded from genomic studies due in part to a lack
of resources supporting their analyses. The 1000 Genomes Project (1kGP) and Human …

Green lean six sigma sustainability–oriented project selection and implementation framework for manufacturing industry

MS Kaswan, R Rathi, JA Garza-Reyes… - International Journal of …, 2023 - emerald.com
Purpose This paper aims to deal with the selection of the sustainability-oriented Green Lean
Six Sigma (GLS) project for the manufacturing industry in the complex decision-making …

Efficient toolkit implementing best practices for principal component analysis of population genetic data

F Privé, K Luu, MGB Blum, JJ McGrath… - …, 2020 - academic.oup.com
Motivation Principal component analysis (PCA) of genetic data is routinely used to infer
ancestry and control for population structure in various genetic analyses. However …

Fast and robust ancestry prediction using principal component analysis

D Zhang, R Dey, S Lee - Bioinformatics, 2020 - academic.oup.com
Motivation Population stratification (PS) is a major confounder in genome-wide association
studies (GWAS) and can lead to false-positive associations. To adjust for PS, principal …

[HTML][HTML] Genome-wide analyses identify 21 infertility loci and over 400 reproductive hormone loci across the allele frequency spectrum

SS Venkatesh, LBL Wittemans, DS Palmer, NA Baya… - medRxiv, 2024 - ncbi.nlm.nih.gov
Genome-wide association studies (GWASs) may help inform treatments for infertility, whose
causes remain unknown in many cases. Here we present GWAS meta-analyses across six …

Double Descent: Understanding Linear Model Estimation of Nonidentifiable Parameters and a Model for Overfitting

R Christensen - arXiv preprint arXiv:2408.13235, 2024 - arxiv.org
We consider ordinary least squares estimation and variations on least squares estimation
such as penalized (regularized) least squares and spectral shrinkage estimates for …

Adjusting systematic bias in high dimensional principal component scores

S Jung - Statistica Sinica, 2022 - JSTOR
Principal component analysis continues to be a powerful tool for the dimension reduction of
high-dimensional data. We assume a variance-diverging model and use the high-dimension …

Adaptive adjustment method of intelligent industrial product dimension accuracy

K Yang - International Journal of Product Development, 2022 - inderscienceonline.com
In order to overcome the problems of low precision and long time in the traditional method of
adjusting the accuracy of external dimensions, this paper proposes an adaptive adjusting …

Genomics and Phenomics of Obsessive-Compulsive and Related Disorders

F Ivankovic - 2022 - search.proquest.com
Tourette syndrome (TS) and obsessive-compulsive disorder (OCD) are neuropsychiatric
disorders with onset in childhood affecting 0.6% and 2.3% of people, respectively. TS and …

Novel Statistical Learning Methods for High-Dimensional Complex Biomedical Data Analysis

D Zhang - 2021 - deepblue.lib.umich.edu
Over the past decades, biomedical data have grown rapidly both in dimension and in
complexity. Traditional statistical models often lack the power of detecting the nonlinear …