We have examined the crystal structures and structural phase transitions of the deuterated,
partially deuterated and hydrogenous organic-inorganic hybrid perovskite methyl …

The coronaviral spike is the dominant viral antigen and the target of neutralizing antibodies.
We show that SARS-CoV-2 spike binds biliverdin and bilirubin, the tetrapyrrole products of …

Refinement of macromolecular X-ray crystal structures involves using complex software with
hundreds of different settings. The complexity of underlying concepts and the sheer amount …

The translation–libration–screw-rotation (TLS) model of rigid-body harmonic displacements
introduced in crystallography by Schomaker and Trueblood [On the rigid-body motion of …

Survival of motor neuron (SMN) functions in diverse biological pathways via recognition of
symmetric dimethylarginine (Rme2s) on proteins by its Tudor domain, and deficiency of …

Small-molecule inhibitors of bromodomain and extra terminal proteins (BET), including
BRD2, BRD3, and BRD4 proteins have therapeutic potential for the treatment of human …

Sirtuins are NAD+-dependent protein deacetylases that regulate metabolism and aging-
related processes. Sirt2 is the only cytoplasmic isoform among the seven mamalian Sirtuins …

SETDB1 is an essential H3K9 methyltransferase involved in silencing of retroviruses and
gene regulation. We show here that its triple Tudor domain (3TD) specifically binds to doubly …

Atomic resolution crystallographic studies of streptavidin and its biotin complex have been
carried out at 1.03 and 0.95 Å, respectively. The wild-type protein crystallized with a tetramer …

Cytosine methylation is a well-characterized epigenetic mark and occurs at both CG and
non-CG sites in DNA. Both methylated CG (mCG)-and mCH (H= A, C, or T)-containing …