Olfactory receptor (OR) proteins interact with odorant molecules in the nose, initiating a
neuronal response that triggers the perception of a smell. The OR family is one of the largest …

The classic notion that humans are microsmatic animals was born from comparative
anatomy studies showing the reduction in the size of both the olfactory bulbs and the limbic …

Olfactory ensheathing cells (OECs) continuously support the regeneration of olfactory
receptor neurons (ORNs). In addition, OECs promote regeneration of neurons within the …

Olfactory receptors are the largest group of orphan G protein-coupled receptors with an
infinitely small number of agonists identified out of thousands of odorants. The de-orphaning …

FoxG1 is an evolutionarily conserved, winged-helix transcriptional repressor that maintains
progenitor cells in the vertebrate forebrain. How the activity of FoxG1 is regulated is not …

The rodent olfactory epithelium (OE) is capable of prolonged neurogenesis, beginning at
E10 in the embryo and continuing throughout adulthood. Significant progress has been …

Neuronal apoptosis is important in the developmental sculpting of a normal nervous system
and also in the loss of neurons caused by neurodegenerative disease, ischemia or trauma …

The olfactory epithelium (OE) regenerates after injury via two types of tissue stem cells:
active globose cells (GBCs) and dormant horizontal basal cells (HBCs). HBCs are roused to …

The olfactory receptor (OR) genes are the largest mammalian gene family and are
expressed in a monogenic and monoallelic fashion in olfactory neurons. Using a high …

Experiments with sciatic nerve lesions and spinal cord contusion injury demonstrate that the
retinoic acid (RA) signaling cascade is activated by these traumatic events. In both cases the …