CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement

C Li, E Brant, H Budak, B Zhang - Journal of Zhejiang University-SCIENCE …, 2021 - Springer
Since it was first recognized in bacteria and archaea as a mechanism for innate viral
immunity in the early 2010s, clustered regularly interspaced short palindromic repeats …

Application of CRISPR/Cas9 in crop quality improvement

Q Liu, F Yang, J Zhang, H Liu, S Rahman… - International Journal of …, 2021 - mdpi.com
The various crop species are major agricultural products and play an indispensable role in
sustaining human life. Over a long period, breeders strove to increase crop yield and …

Application of gene editing for climate change in agriculture

NG Karavolias, W Horner, MN Abugu… - Frontiers in Sustainable …, 2021 - frontiersin.org
Climate change imposes a severe threat to agricultural systems, food security, and human
nutrition. Meanwhile, efforts in crop and livestock gene editing have been undertaken to …

[HTML][HTML] The present and potential future methods for delivering CRISPR/Cas9 components in plants

D Sandhya, P Jogam, VR Allini, S Abbagani… - Journal of Genetic …, 2020 - Elsevier
Background CRISPR/Cas9 genome editing technology is a DNA manipulation tool for trait
improvement. This technology has been demonstrated and successfully applied to edit the …

CRISPR-based genome editing for nutrient enrichment in crops: a promising approach toward global food security

D Kumar, A Yadav, R Ahmad, UN Dwivedi… - Frontiers in …, 2022 - frontiersin.org
The global malnutrition burden imparts long-term developmental, economic, social, and
medical consequences to individuals, communities, and countries. The current …

Transgenic and genome-edited fruits: background, constraints, benefits, and commercial opportunities

M Lobato-Gómez, S Hewitt, T Capell… - Horticulture …, 2021 - academic.oup.com
Breeding has been used successfully for many years in the fruit industry, giving rise to most
of today's commercial fruit cultivars. More recently, new molecular breeding techniques have …

CRISPR-mediated engineering across the central dogma in plant biology for basic research and crop improvement

D Pramanik, RM Shelake, MJ Kim, JY Kim - Molecular Plant, 2021 - cell.com
The central dogma (CD) of molecular biology is the transfer of genetic information from DNA
to RNA to protein. Major CD processes governing genetic flow include the cell cycle, DNA …

Genome-edited foods

A Tuncel, C Pan, T Sprink, R Wilhelm… - Nature Reviews …, 2023 - nature.com
Genome editing can transform agriculture and shape the future of food by improving crop
yields and animal productivity, which in turn can help to achieve food security for the …

Metabolic engineering of plant secondary metabolites: prospects and its technological challenges

A Mipeshwaree Devi, K Khedashwori Devi… - Frontiers in Plant …, 2023 - frontiersin.org
Plants produce a wide range of secondary metabolites that play vital roles for their primary
functions such as growth, defence, adaptations or reproduction. Some of the plant …

CRISPR/dCas9-based systems: mechanisms and applications in plant sciences

CKS Karlson, SN Mohd-Noor, N Nolte, BC Tan - Plants, 2021 - mdpi.com
RNA-guided genomic transcriptional regulation tools, namely clustered regularly
interspaced short palindromic repeats interference (CRISPRi) and CRISPR-mediated gene …