The kidneys play a key role in maintaining total body homeostasis. The complexity of this
task is reflected in the unique architecture of the organ. Ureteral obstruction greatly affects …

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the isoenzymes COX-1 and COX-2 of
cyclooxygenase (COX). Renal side effects (eg, kidney function, fluid and urinary electrolyte …

We studied here the independent roles of angiotensin II and aldosterone in regulating the
sodium chloride cotransporter (NCC) of the distal convoluted tubule. We adrenalectomized …

The distal convoluted tubule (DCT) Na+-Cl− cotransporter (NCC), the target of thiazide
diuretics, is responsible for the reabsorption of 5–10% of filtered NaCl. The aim of this study …

Study Type–Therapy (case series) Level of Evidence 4 What's known on the subject? and
What does the study add? The pathophysiology of post‐renal acute kidney injury (PR‐AKI) …

Over recent years routine ultrasound scanning has identified increasing numbers of
neonates as having hydronephrosis and pelvi-ureteric junction obstruction (PUJO). This …

Arginine-vasopressin (AVP) stimulates the redistribution of water channels, aquaporin-2
(AQP2) from intracellular vesicles into the plasma membrane of renal collecting duct …

838 Aquaporins in the female reproductive system of mammals Cui Zhu1,2, Zongyong Jiang1,
Fuller W. Bazer2, Gregory A. Johnson3, Page 1 [Frontiers in Bioscience, Landmark, 20 …

Abstract Aquaporin‐2 (AQP2), the vasopressin‐regulated water channel of the renal
collecting duct, is dysregulated in numerous disorders of water balance in people and …

The discovery of aquaporin‐1 (AQP1) explained the long‐standing biophysical question of
how water specifically crosses biological membranes. These studies led to the identification …