Nonsteroidal antiinflammatory drugs (NSAIDs) appear to reduce the risk of developing
cancer. One mechanism through which NSAIDs act to reduce carcinogenesis is to inhibit the …

Most solid tumors express the cyclooxygenase-2 (COX-2) protein, a target of NSAIDs. COX-
2 overexpression in tumorsis considered a predictor of more advanced stage disease and of …

Increasing interest in the use of phytochemicals to reduce prostate cancer led us to
investigate 2 potential agents, curcumin and resveratrol as preventive agents. However …

Purpose: Multiple studies have indicated that cyclooxygenase-2 (COX-2) inhibitors may
prevent colon cancer, which is one of the leading causes of cancer death in the western …

Epidemiological and clinical studies suggest that non-steroidal anti-inflammatory drugs
(NSAIDs), including cyclooxygenase (COX)-2 selective inhibitors, reduce the risk of …

Abstract Purpose: Selective cyclooxygenase-2 (COX-2) inhibitors may suppress
carcinogenesis by both COX-2-dependent and COX-2-independent mechanisms. The …

Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is the only non-steroidal anti-
inflammatory drug so far which has been approved by the FDA for adjuvant treatment of …

Epidemiological studies and clinical observations suggest that nonsteroidal anti-
inflammatory drugs and certain selective cyclooxygenase (COX)-2 inhibitors may reduce the …

Abstract Background Selective cyclooxygenase (COX)-2 inhibitors elicit anti-proliferative
responses in various tumours, however the underlying anti-tumour mechanisms are unclear …

To characterize the radiation-enhancing effects on human cancer cells and underlying
mechanisms of celecoxib, a cyclooxygenase (COX)-2 selective inhibitor, and to ascertain …