When life‐sustaining treatments (LST) are no longer effective or consistent with patient
preferences, limitations may be set so that LSTs are withdrawn or withheld from the patient …

Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden
for patients, families, and society worldwide. As part of the Curing Coma Campaign, the …

Background Brain injury is reportedly the main cause of death for patients resuscitated after
out-of-hospital cardiac arrest (OHCA). However, the majority may actually die following …

An increasing number of patients are successfully resuscitated from cardiac arrest (CA) and
subsequently treated in an intensive care unit due to unconsciousness. Approximately half …

Background and Purpose—We aimed to determine whether subjects aged≤ 70 years who
were treated with intravenous glyburide (RP-1127; BIIB093; glibenclamide) would have …

Objective Survivors of prolonged (> 2 weeks) post–cardiac arrest (CA) coma are expected to
remain permanently disabled. We aimed to investigate 3 outlier patients who ultimately …

Background Among patients successfully resuscitated after an out-of-hospital cardiac arrest
(OHCA), 10% to 15% evolve toward brain death (BD), thus becoming potential organ …

Background The objective of this study is to describe incidence and factors associated with
early withdrawal of life-sustaining therapies based on presumed poor neurologic prognosis …

Introduction Most successfully resuscitated cardiac arrest patients do not survive to hospital
discharge. Many have withdrawal of life sustaining therapy (WLST) as a result of the …

Aim To determine the timing and modes of death of children admitted to a pediatric critical
care unit (PICU) of a tertiary care center after an out-of-hospital cardiac arrest (OHCA) …