Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

Abstract The recently introduced Oxford Nanopore MinION platform generates DNA
sequence data in real-time. This has great potential to shorten the sample-to-results time …

The advances of high-throughput sequencing offer an unprecedented opportunity to study
genetic variation. This is challenged by the difficulty of resolving variant calls in repetitive …

Background Traditional genome alignment methods consider sequence alignment as a
variation of the string edit distance problem, and perform alignment by matching characters …

Methods for measuring genetic distances in phylogenetics are known to be sensitive to the
evolutionary model assumed. However, there is a lack of established methodology to …

Sequence Alignment is one of the most widely and successfully employed computational
biology tools. Despite their wide spread acceptance these algorithms rely on biologically …

Information Theoretic Approaches to Biological Sequence Analyses Clayton School of
Information Technology Monash University Page 1 Information Theoretic Approaches to …