Strain and elasticity imaging in compression optical coherence elastography: the two‐decade perspective and recent advances

VY Zaitsev, AL Matveyev, LA Matveev… - Journal of …, 2021 - Wiley Online Library
Quantitative mapping of deformation and elasticity in optical coherence tomography has
attracted much attention of researchers during the last two decades. However, despite …

Introduction to optical coherence elastography: tutorial

M Singh, F Zvietcovich, KV Larin - JOSA A, 2022 - opg.optica.org
Optical coherence elastography (OCE) has seen rapid growth since its introduction in 1998.
The past few decades have seen tremendous advancements in the development of OCE …

Histological validation of in vivo assessment of cancer tissue inhomogeneity and automated morphological segmentation enabled by Optical Coherence Elastography

AA Plekhanov, MA Sirotkina, AA Sovetsky… - Scientific reports, 2020 - nature.com
We present a non-invasive (albeit contact) method based on Optical Coherence
Elastography (OCE) enabling the in vivo segmentation of morphological tissue constituents …

OCT-elastography-based optical biopsy for breast cancer delineation and express assessment of morphological/molecular subtypes

EV Gubarkova, AA Sovetsky, VY Zaitsev… - Biomedical optics …, 2019 - opg.optica.org
Application of compressional optical coherence elastography (OCE) for delineation of tumor
and peri-tumoral tissue with simultaneous assessment of morphological/molecular subtypes …

Manually-operated compressional optical coherence elastography with effective aperiodic averaging: demonstrations for corneal and cartilaginous tissues

AA Sovetsky, AL Matveyev, LA Matveev… - Laser Physics …, 2018 - iopscience.iop.org
Compressional elastography in optical coherence tomography (OCT) is based on relating
the sought spatial distribution of stiffness with initially reconstructed strain distribution by …

Towards targeted colorectal cancer biopsy based on tissue morphology assessment by compression optical coherence elastography

AA Plekhanov, MA Sirotkina, EV Gubarkova… - Frontiers in …, 2023 - frontiersin.org
Identifying the precise topography of cancer for targeted biopsy in colonoscopic examination
is a challenge in current diagnostic practice. For the first time we demonstrate the use of …

Nonlinear elasticity assessment with optical coherence elastography for high-selectivity differentiation of breast cancer tissues

EV Gubarkova, AA Sovetsky, LA Matveev, AL Matveyev… - Materials, 2022 - mdpi.com
Soft biological tissues, breast cancer tissues in particular, often manifest pronounced
nonlinear elasticity, ie, strong dependence of their Young's modulus on the applied stress …

Full-optical method of local stress standardization to exclude nonlinearity-related ambiguity of elasticity estimation in compressional optical coherence elastography

AA Sovetsky, AL Matveyev, LA Matveev… - Laser Physics …, 2020 - iopscience.iop.org
Pronounced elastic nonlinearity intrinsic to many biological tissues makes the Young's
modulus (stiffness) of the tissue strongly dependent on the current strain and stress. The …

In vivo assessment of functional and morphological alterations in tumors under treatment using OCT-angiography combined with OCT-elastography

MA Sirotkina, EV Gubarkova, AA Plekhanov… - Biomedical optics …, 2020 - opg.optica.org
Emerging methods of anti-tumor therapies require new approaches to tumor response
evaluation, especially enabling label-free diagnostics and in vivo utilization. Here, to assess …

Diagnostic accuracy of cross-polarization OCT and OCT-elastography for differentiation of breast cancer subtypes: comparative study

EV Gubarkova, EB Kiseleva, MA Sirotkina… - Diagnostics, 2020 - mdpi.com
The possibility to assess molecular-biological and morphological features of particular
breast cancer types can improve the precision of resection margin detection and enable …