Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
common cause of non-traumatic neurological disability in young adults. The likelihood for an …

Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …

Multiple sclerosis (MS) is a complex trait in which allelic variation in the MHC class II region
exerts the single strongest effect on genetic risk. Epidemiological data in MS provide strong …

Multiple sclerosis (MS) is an autoimmune demyelinating disease and a common cause of
neurological disability in young adults. The modest heritability of MS reflects complex …

Multiple sclerosis (MS), a common central nervous system inflammatory disease, has a
major heritable component. Susceptibility is associated with the MHC class II region …

Major histocompatibility complex (MHC) class II molecules are central to adaptive immune
responses and maintenance of self-tolerance. Since the early 1970s, the MHC class II …

The genetics of complex disease is entering a new and exciting era. The exponentially
growing knowledge and technological capabilities emerging from the human genome …

Multiple Sclerosis (MS) is the most common demyelinating disease of the central nervous
system. Although the etiology and the pathogenesis of MS has been extensively …

Genes encoding antigen‐presenting molecules within the human major histocompatibility
complex (MHC) account for the highest component of genetic risk for many neurological …

Necrotizing meningoencephalitis (NME) is a disorder of Pug Dogs that appears to have an
immune etiology and high heritability based on population studies. The present study was …