Thyroid hormone receptor α1: a novel regulator of thyroid cancer cell differentiation

E Hwang, WKL Doolittle, YJ Zhu, X Zhu, L Zhao, Y Yu… - Oncogene, 2023 - nature.com
Thyroid hormone receptor α1 (TRα1) mediates the genomic actions of thyroid hormone (T3).
The biology of TRα1 in growth and development has been well studied, but the functional …

Overlapping action of T3 and T4 during Xenopus laevis development

A Tribondeau, D Du Pasquier, M Benchouaia… - Frontiers in …, 2024 - frontiersin.org
Thyroid hormones are involved in many biological processes such as neurogenesis,
metabolism, and development. However, compounds called endocrine disruptors can alter …

Impact of the thyroid hormone T3 and its nuclear receptor TRα1 on colon cancer stem cell phenotypes and response to chemotherapies

MV Giolito, S Bodoirat, T La Rosa, M Reslinger… - Cell Death & …, 2024 - nature.com
Colorectal cancers (CRCs) are highly heterogeneous and show a hierarchical organization,
with cancer stem cells (CSCs) responsible for tumor development, maintenance, and drug …

Integrated analysis of intestinal microbiota and transcriptome reveals that a coordinated interaction of the endocrine, immune system and gut microbiota response to …

G Liao, W Wang, J Yu, J Li, Y Yan, H Liu, B Chen… - Developmental & …, 2024 - Elsevier
Due to the ongoing global warming, the risk of heatwaves in the oceans is continuously
increasing while our understanding of the physiological response of Litopenaeus vannamei …

Casual associations of thyroid function with inflammatory bowel disease and the mediating role of cytokines

S Wu, J Yi, B Wu - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Previous observational epidemiological studies have suggested a potential
association between thyroid function and inflammatory bowel disease (IBD). However, the …

Identification of a pyroptosis-related prognostic model for colorectal cancer and validation of the core gene SPTBN5

G Li, P Wang, X Feng, Y Li - Discover Oncology, 2024 - Springer
Background Pyroptosis, an emerging type of programmed cell death. The mechanisms of
pyroptosis mainly include inflammasome-activated pyroptosis and non-inflammasome …