Squamous cell carcinoma of the oral tongue (SCCOT) is one of the most prevalent tumors of
the head and neck region. Despite advances in treatment, the survival of patients with …

Oral squamous cell carcinoma (OSCC) patients have a low 5-year survival rate and poor
prognosis. To improve survival and prognosis, the causes and processes involved in lesion …

The solid tumour microenvironment includes nerve fibres that arise from the peripheral
nervous system,. Recent work indicates that newly formed adrenergic nerve fibres promote …

The fact that the identity of the cells that initiate metastasis in most human cancers is
unknown hampers the development of antimetastatic therapies. Here we describe a …

Although nutrient-starvation therapies can elicit strong anti-tumor effects in multiple
carcinomas, it has been convincingly demonstrated that cancer cells exploit the tumor …

Fatty acid uptake and altered metabolism constitute hallmarks of metastasis,, yet evidence of
the underlying biology, as well as whether all dietary fatty acids are prometastatic, is lacking …

Angiogenesis is a key process that allows nutrient uptake and cellular trafficking and is
coopted in cancer to enable tumor growth and metastasis. Recently, extracellular vesicles …

Fucoidan is a dietary brown algae-derived fucose-rich polysaccharide. However, the
anticancer effects of fucoidan for oral cancer treatment remain unclear, particularly in terms …

“Warburg effect”, the enhanced glycolysis or aerobic glycolysis, confers cancer cells the
ability to survive and proliferate even under stressed conditions. In this study, we explored …

Preclinical animal models of oral squamous cell carcinoma (OSCC) have been extensively
studied in recent years. Investigating the pathogenesis and potential therapeutic strategies …