Palladium‐catalyzed coupling reactions of aryl chlorides

AF Littke, GC Fu - Angewandte Chemie International Edition, 2002 - Wiley Online Library
Collectively, palladium‐catalyzed coupling reactions represent some of the most powerful
and versatile tools available to synthetic organic chemists. Their widespread popularity …

Synthesis and functionalization of indoles through palladium-catalyzed reactions

S Cacchi, G Fabrizi - Chemical reviews, 2005 - ACS Publications
The substituted indole nucleus [indole is the acronym from indigo (the natural dye) and
oleum (used for the isolation)] is a structural component of a vast number of biologically …

<? ACS-CT-START-Insert?> Update 1 of:<? ACS-CT-END-Insert?> Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions

S Cacchi, G Fabrizi - Chemical Reviews, 2011 - ACS Publications
The substituted indole nucleus [indole is the acronym fromindigo (the natural dye) and
oleum (used for the isolation)] is a structural component of a vast number of biologically …

Pyrimidine as constituent of natural biologically active compounds

IM Lagoja - Chemistry & Biodiversity, 2005 - Wiley Online Library
This review describes the various manifestations of the pyrimidine system (alkylated,
glycosylated, benzo‐annelated.). These comprise pyrimidine nucleosides as well as …

Palladiumkatalysierte Kupplungen von Arylchloriden

AF Littke, GC Fu - Angewandte Chemie, 2002 - Wiley Online Library
Palladiumkatalysierte Kupplungen gehören zu den leistungsfähigsten und vielseitigsten
Reaktionen, die dem organischen Chemiker für die Synthese zur Verfügung stehen. Ihre …

Variolins and related alkaloids

SR Walker, EJ Carter, BC Huff, JC Morris - Chemical reviews, 2009 - ACS Publications
The phosphorylation of proteins on serine, threonine, and tyrosine residues by the 518
protein kinases encoded in the human genome constitutes one of the major mechanisms …

Synthesis and antitumor activity of 2, 5-bis (3′-indolyl)-furans and 3, 5-bis (3′-indolyl)-isoxazoles, nortopsentin analogues

P Diana, A Carbone, P Barraja, G Kelter… - Bioorganic & medicinal …, 2010 - Elsevier
A series of novel 2, 5-bis (3′-indolyl) furans and 3, 5-bis (3′-indolyl) isoxazoles were
synthesized as antitumor agents. The antiproliferative activity was evaluated in vitro toward …

Synthesis and reactivity of 7-azaindole (1H-pyrrolo [2, 3-b] pyridine)

F Popowycz, S Routier, B Joseph, JY Mérour - Tetrahedron, 2007 - Elsevier
Contrary to indoles, the 7-azaindole (1H-pyrrolo [2, 3-b] pyridine) nucleus is present only in
a few natural products such as alkaloids from the variolin family. Nevertheless, 7-azaindole …

Kinase inhibitors of marine origin

SB Bharate, SD Sawant, PP Singh… - Chemical …, 2013 - ACS Publications
The ocean occupies three-fourths of the Earth's surface and hosts approximately 80% of all
living species. In fact, some areas of the sea such as coral reefs possess a biodiversity …

A comprehensive review of N-heterocycles as cytotoxic agents

D Kumar, S Kumar Jain - Current Medicinal Chemistry, 2016 - ingentaconnect.com
Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …