Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

A pharmacophore system has been found as 1, 2, 3‐triazole, a five‐membered heterocycle
ring with nitrogen heteroatoms. These heterocyclic compounds can be produced using …

Nature products have been extensively used in the discovery and development of new
drugs, as the most important source of drugs. The triazole ring is one of main …

The need to overcome ever-increasing cases of antifungal resistance and circumvent side
effects and drug interactions related to currently available drugs has impelled the demand to …

Simple Summary Coumarins are a large family of benzopyrones, and more than 1300
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …

The anthropogenic influence on the environment, exemplified by phenomena such as global
warming, ozone layer depletion, glacier melting, biodiversity loss, and significant shifts in …

Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the
molecular diversity and unique functions of complex natural products up to now. It enables …

Given the importance of the highly reactive nature and attractiveness of coumarins as a
precursor of natural products and pharmacological agents, tremendous efforts have been …

Natural products play a key role in the history of human drug discovery, and especially for
the anticancer agents. Copper (I)-catalyzed alkyne-azide [3+ 2] cycloaddition (CuAAC) …

Currently, in hospitals and community health centers, microbial infections are highly
common diseases and are a leading cause of death worldwide. Antibiotics are generally …