Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue that is organized into cell layers with microcircuits working in parallel and together to encode …
T Euler, S Haverkamp, T Schubert… - Nature Reviews …, 2014 - nature.com
Retinal bipolar cells are the first'projection neurons' of the vertebrate visual system—all of the information needed for vision is relayed by this intraretinal connection. Each of the at …
GW Schwartz, H Okawa, FA Dunn, JL Morgan… - Nature …, 2012 - nature.com
Understanding a sensory system implies the ability to predict responses to a variety of inputs from a common model. In the retina, this includes predicting how the integration of signals …
The activity-dependent rules that govern the wiring of GABAergic interneurons are not well understood. Chandelier cells (ChCs) are a type of GABAergic interneuron that control …
CL Rees, K Moradi, GA Ascoli - Trends in neurosciences, 2017 - cell.com
Although the importance of network connectivity is increasingly recognized, identifying synapses remains challenging relative to the routine characterization of neuronal …
Electrical and chemical synapses coexist in circuits throughout the CNS. Yet, it is not well understood how electrical and chemical synaptic transmission interact to determine the …
MJ Fitzpatrick, D Kerschensteiner - Progress in Retinal and Eye Research, 2023 - Elsevier
Vision begins in the retina, whose intricate neural circuits extract salient features of the environment from the light entering our eyes. Neurodegenerative diseases of the retina (eg …
Highlights•Synaptic activity drives the formation of specific synapses in the retina.• Neurotransmitter induces the formation of spines in developing cortical neurons.•Axons are …
FM Rodríguez-Tornos, CG Briz, LA Weiss… - Neuron, 2016 - cell.com
Neuronal subtype-specific transcription factors (TFs) instruct key features of neuronal function and connectivity. Activity-dependent mechanisms also contribute to wiring and …