Background and Objective: Primary immunodeficiency diseases (PIDs) are a group of more
than 350 disorders affecting distinct components of the innate and adaptive immune …

Objectives: Identify the different etiologies and epidemiology of lymphocytosis. Review the
evaluation of patients with lymphocytosis. Outline the treatment and management options …

High Frequency of Thyroid Disorders in Patients Presenting W... : Medicine High Frequency of
Thyroid Disorders in Patients Presenting With Neutropenia to an Outpatient Hematology Clinic …

Flow cytometry diagnostic practices can detect very low levels of clonal B cells in the
peripheral blood. In the absence of clinical symptoms, cytopenia or organomegaly, the small …

Background English bulldogs disproportionally develop an expansion of small B‐cells,
which has been interpreted as B‐cell chronic lymphocytic leukemia (BCLL). However …

Acquired clonal chromosomal abnormalities (CAs) are usually considered to be disease-
related. However, when a CA of this type is the only abnormality present (and especially in …

Lymphoid aggregates in bone marrow specimens are a relatively frequent finding that may
pose a diagnostic challenge for a pathologist. The distinction between reactive and …

Persistent polyclonal B-cell lymphocytosis (PPBL) is a rare disorder, which mostly affects
middle-aged women and is associated with smoking. 1 It is characterized by the persistent …

Background and aims The diagnosis of persistent polyclonal B-cell lymphocytosis (PPBL) is
often challenging because of the lack of features and the overlap with the peripheral …

Introduction: Persistent polyclonal B-cell lymphocytosis (PPBL) is a rare and still poorly
understood entity, with 90% of cases occurring in female smokers. Patients often appear …