DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms

J Yao, E Bergsland, R Aggarwal, A Aparicio… - The …, 2022 - academic.oup.com
Introduction Neuroendocrine neoplasms (NEN) are heterogeneous malignancies that can
arise at almost any anatomical site and are classified as biologically distinct well …

Management of gastrointestinal neuroendocrine tumors

R Wang, R Zheng-Pywell, HA Chen… - Clinical Medicine …, 2019 - journals.sagepub.com
Neuroendocrine neoplasms (NENs) are derived from neuroendocrine cell system and can
have benign or malignant characteristics. They are rare tumors, but have been increasing in …

Surufatinib in advanced pancreatic neuroendocrine tumours (SANET-p): a randomised, double-blind, placebo-controlled, phase 3 study

J Xu, L Shen, C Bai, W Wang, J Li, X Yu, Z Li… - The Lancet …, 2020 - thelancet.com
Background Surufatinib showed superior efficacy in extrapancreatic neuroendocrine
tumours (NETs) in the phase 3 SANET-ep study. In SANET-p, we aimed to assess the …

Incidence and survival of neuroendocrine neoplasia in England 1995–2018: A retrospective, population-based study

BE White, B Rous, K Chandrakumaran… - The Lancet Regional …, 2022 - thelancet.com
Background Neuroendocrine neoplasia (NEN) incidence is rising internationally. We aimed
to evaluate the epidemiology of NEN in England and examine changes in survival over time …

Trends of incidence and prognosis of gastric neuroendocrine neoplasms: a study based on SEER and our multicenter research

P Hu, J Bai, M Liu, J Xue, T Chen, R Li, X Kuai, H Zhao… - Gastric Cancer, 2020 - Springer
Background To investigate the recent epidemiological trends of gastric neuroendocrine
neoplasms (GNENs) and establish a new tool to estimate the prognosis of gastric …

[HTML][HTML] The rising incidence of early-onset colorectal cancer

LF Tanaka, SH Figueroa, V Popova… - Deutsches Ärzteblatt …, 2023 - ncbi.nlm.nih.gov
Background The incidence of early-onset (diagnosis before age 50) colorectal cancer (EO-
CRC) is increasing in some high-income countries. The present study analyzed this trend in …

Systemic treatment of gastroenteropancreatic neuroendocrine carcinoma

K Mollazadegan, S Welin, J Crona - Current treatment options in oncology, 2021 - Springer
Opinion statement Treatment recommendations for advanced gastroenteropancreatic
neuroendocrine carcinomas (GEP-NEC) are based on uncontrolled, mainly retrospective …

Simultaneous detection of multiple neuroendocrine tumor markers in patient serum with an ultrasensitive and antifouling electrochemical immunosensor

X Liu, Y Li, L He, Y Feng, H Tan, X Chen… - Biosensors and …, 2021 - Elsevier
Neuroendocrine tumors (NETs) are rare heterogeneous tumors that are often misdiagnosed
and mistreated. Most NETs patients are diagnosed as advanced. Early on-time detection of …

Current treatments and future potential of surufatinib in neuroendocrine tumors (NETs)

J Xu - Therapeutic advances in medical oncology, 2021 - journals.sagepub.com
Neuroendocrine tumors (NETs) are rare, heterogeneous, often indolent tumors that
predominantly originate in the lungs and gastrointestinal tract. An understanding of the …

Gastroenteropancreatic neuroendocrine tumors

CJ Fernandes, G Leung, JR Eads… - Gastroenterology …, 2022 - gastro.theclinics.com
Neuroendocrine tumors (NETs) are an uncommon, heterogeneous group of tumors arising
from cells of neuroendocrine origin, which can be found at multiple sites throughout the …