Synthetic Oplophorus luciferases with enhanced light output
(57) ABSTRACT A polynucleotide encoding a modified luciferase polypep tide. The modified
luciferase polypeptide has at least 60% amino acid sequence identity to a wild-type …
luciferase polypeptide has at least 60% amino acid sequence identity to a wild-type …
Imidazo [1, 2-α] pyrazine derivatives
DH Klaubert, P Meisenheimer, J Unch - US Patent 8,809,529, 2014 - Google Patents
2019-04-03 Assigned to JPMORGAN CHASE BANK, NA, AS COLLATERAL AGENT
reassignment JPMORGAN CHASE BANK, NA, AS COLLATERAL AGENT SECURITY …
reassignment JPMORGAN CHASE BANK, NA, AS COLLATERAL AGENT SECURITY …
Coelenterazine derivatives and methods of using same
DH Klaubert, P Meisenheimer, J Unch… - US Patent …, 2016 - Google Patents
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Squirrell et al. 5.998. 204 A 12/1999 Tsien et al. 6,132,983 A 10, 2000 Lowe et al. 6,171,808 …
Permuted and nonpermuted luciferase biosensors
B Binkowski, F Fan, S Wigdal, KV Wood… - US Patent …, 2016 - Google Patents
2007-08-17 Assigned to PROMEGA CORPORATION reassignment PROMEGA
CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Activation of bioluminescence by structural complementation
Provided herein are compositions and methods for the assembly of a bioluminescent
complex from two or more non-luminescent (eg, substantially non-luminescent) peptide …
complex from two or more non-luminescent (eg, substantially non-luminescent) peptide …
Luciferase biosensors for cAMP
2009-09-17 Assigned to PROMEGA CORPORATION reassignment PROMEGA
CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer
The present invention provides compositions and methods for detection and analysis of
intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are …
intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are …
Pro-substrates for live cell applications
US9927430B2 - Pro-substrates for live cell applications - Google Patents US9927430B2 -
Pro-substrates for live cell applications - Google Patents Pro-substrates for live cell …
Pro-substrates for live cell applications - Google Patents Pro-substrates for live cell …
Quinone-masked probes as labeling reagents for cell uptake measurements
W Zhou, P Meisenheimer, S Duellman, D Ma… - US Patent …, 2017 - Google Patents
US9790537B2 - Quinone-masked probes as labeling reagents for cell uptake
measurements - Google Patents US9790537B2 - Quinone-masked probes as labeling …
measurements - Google Patents US9790537B2 - Quinone-masked probes as labeling …