Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

[HTML][HTML] Therapeutic strategies against bacterial biofilms

Y Bi, G Xia, C Shi, J Wan, L Liu, Y Chen, Y Wu… - Fundamental …, 2021 - Elsevier
The emergence of multi-drug resistance makes bacterial infection a major threat to public
health and economy. The formation of bacterial biofilms is one of the main reasons of …

An update on recent developments in the prevention and treatment of Staphylococcus aureus biofilms

MK Suresh, R Biswas, L Biswas - International Journal of Medical …, 2019 - Elsevier
Staphylococcus aureus (S. aureus) readily forms biofilms on prosthetic devices such as the
pacemakers, heart valves, orthopaedic implants, and indwelling catheters. Its biofilms are …

Injectable Lignin-co-Gelatin Cryogels with Antioxidant and Antibacterial Properties for Biomedical Applications

T Abdullah, T Colombani, T Alade… - …, 2021 - ACS Publications
For several biomedical applications, it is essential to develop novel bioactive materials.
Such biomaterials could potentially improve wound healing, prevent infections, or be used in …

Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms

E Teirlinck, R Xiong, T Brans, K Forier, J Fraire… - Nature …, 2018 - nature.com
Hindered penetration of antibiotics through biofilms is one of the reasons for the alarming
increase in bacterial tolerance to antibiotics. Here, we investigate the potential of laser …

The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung

S O'Brien, JL Fothergill - FEMS microbiology letters, 2017 - academic.oup.com
Pseudomonas aeruginosa is a major pathogen in the lungs of cystic fibrosis (CF) patients.
However, it is now recognised that a diverse microbial community exists in the airways …

A review on basic biology of bacterial biofilm infections and their treatments by nanotechnology-based approaches

D Banerjee, PM Shivapriya, PK Gautam… - Proceedings of the …, 2020 - Springer
Biofilms are responsible for causing 80% of human infections including chronic infections
like-cystic fibrosis, endocarditis and osteomyelitis. The growing ability of the biofilm to resist …

Chitosan-Based Hydrogel for the Dual Delivery of Antimicrobial Agents Against Bacterial Methicillin-Resistant Staphylococcus aureus Biofilm-Infected Wounds

VO Fasiku, CA Omolo, N Devnarain, UH Ibrahim… - ACS …, 2021 - ACS Publications
Chronic wound infections caused by antibiotic-resistant bacteria have become a global
health concern. This is attributed to the biofilm-forming ability of bacteria on wound surfaces …

Nanomaterials for treating bacterial biofilms on implantable medical devices

HM Tran, H Tran, MA Booth, KE Fox, TH Nguyen… - Nanomaterials, 2020 - mdpi.com
Bacterial biofilms are involved in most device-associated infections and remain a challenge
for modern medicine. One major approach to addressing this problem is to prevent the …

Interactions between macrophages and biofilm during Staphylococcus aureus-associated implant infection: difficulties and solutions

M Li, J Yu, G Guo, H Shen - Journal of Innate Immunity, 2023 - karger.com
Staphylococcus aureus (S. aureus) biofilm is the major cause of failure of implant infection
treatment that results in heavy social and economic burden on individuals, families, and …