Regulation of translation via mRNA structure in prokaryotes and eukaryotes
M Kozak - Gene, 2005 - Elsevier
The mechanism of initiation of translation differs between prokaryotes and eukaryotes, and
the strategies used for regulation differ accordingly. Translation in prokaryotes is usually …
the strategies used for regulation differ accordingly. Translation in prokaryotes is usually …
The A–Z of bacterial translation inhibitors
DN Wilson - Critical reviews in biochemistry and molecular biology, 2009 - Taylor & Francis
Protein synthesis is one of the major targets in the cell for antibiotics. This review endeavors
to provide a comprehensive “post-ribosome structure” A–Z of the huge diversity of antibiotics …
to provide a comprehensive “post-ribosome structure” A–Z of the huge diversity of antibiotics …
Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria
The synthesis of mitochondrial OXPHOS complexes is central to cellular metabolism, yet
many molecular details of mitochondrial translation remain elusive. It has been commonly …
many molecular details of mitochondrial translation remain elusive. It has been commonly …
Leaderless transcripts and small proteins are common features of the mycobacterial translational landscape
RNA-seq technologies have provided significant insight into the transcription networks of
mycobacteria. However, such studies provide no definitive information on the translational …
mycobacteria. However, such studies provide no definitive information on the translational …
Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis
Deciphering physiological changes that mediate transition of Mycobacterium tuberculosis
between replicating and nonreplicating states is essential to understanding how the …
between replicating and nonreplicating states is essential to understanding how the …
Protein synthesis by ribosomes with tethered subunits
C Orelle, ED Carlson, T Szal, T Florin, MC Jewett… - Nature, 2015 - nature.com
The ribosome is a ribonucleoprotein machine responsible for protein synthesis. In all
kingdoms of life it is composed of two subunits, each built on its own ribosomal RNA (rRNA) …
kingdoms of life it is composed of two subunits, each built on its own ribosomal RNA (rRNA) …
Selective translation of leaderless mRNAs by specialized ribosomes generated by MazF in Escherichia coli
O Vesper, S Amitai, M Belitsky, K Byrgazov… - Cell, 2011 - cell.com
Escherichia coli (E. coli) mazEF is a stress-induced toxin-antitoxin (TA) module. The toxin
MazF is an endoribonuclease that cleaves single-stranded mRNAs at ACA sequences …
MazF is an endoribonuclease that cleaves single-stranded mRNAs at ACA sequences …
Initiation of mRNA translation in bacteria: structural and dynamic aspects
CO Gualerzi, CL Pon - Cellular and Molecular Life Sciences, 2015 - Springer
Initiation of mRNA translation is a major checkpoint for regulating level and fidelity of protein
synthesis. Being rate limiting in protein synthesis, translation initiation also represents the …
synthesis. Being rate limiting in protein synthesis, translation initiation also represents the …
How hibernation factors RMF, HPF, and YfiA turn off protein synthesis
YS Polikanov, GM Blaha, TA Steitz - Science, 2012 - science.org
Eubacteria inactivate their ribosomes as 100 S dimers or 70 S monomers upon entry into
stationary phase. In Escherichia coli, 100 S dimer formation is mediated by ribosome …
stationary phase. In Escherichia coli, 100 S dimer formation is mediated by ribosome …
Comprehensive analysis of the Corynebacterium glutamicum transcriptome using an improved RNAseq technique
Abstract Background The use of RNAseq to resolve the transcriptional organization of an
organism was established in recent years and also showed the complexity and dynamics of …
organism was established in recent years and also showed the complexity and dynamics of …