This review provides an overview of the clinical issue of poorly controlled postoperative pain
and therapeutic approaches that may help to address this common unresolved health-care …

Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

Define chronic post-surgical pain (CPSP) according to the ICD-11 (International
Classification of Diseases, Eleventh Revision) classification and describe its impact on …

Importance Prolonged opioid use after surgery may be associated with opioid dependency
and increased health care use. However, published studies have reported varying estimates …

The development of chronic pain is considered a major complication after surgery. Basic
science research in animal models helps us understand the transition from acute to chronic …

Background Regional anaesthesia may reduce the rate of persistent postoperative pain
(PPP), a frequent and debilitating condition. This review was originally published in 2012 …

Poor management of post-operative acute pain can contribute to medical complications
including pneumonia, deep vein thrombosis, infection and delayed healing, as well as the …

Background The primary goal of this study was to evaluate patterns in acute postoperative
pain in a mixed surgical patient cohort with the hypothesis that there would be heterogeneity …

Opioid-free anesthesia (OFA) is emerging as a new stimulating research perspective. The
rationale to propose OFA is based on the aim to avoid the negative impact of intraoperative …

Objectives: To investigate the influence of an Acute Pain Service (APS) on the incidence of
chronic postsurgical pain (CPSP). CPSP risk factors include acute postoperative pain …