[HTML][HTML] Comparative statistical analysis of the release kinetics models for nanoprecipitated drug delivery systems based on poly (lactic-co-glycolic acid)
Poly (lactic-co-glycolic acid) is one of the most used polymers for drug delivery systems
(DDSs). It shows excellent biocompatibility, biodegradability, and allows spatio-temporal …
(DDSs). It shows excellent biocompatibility, biodegradability, and allows spatio-temporal …
Preparation of sustained release apremilast-loaded PLGA nanoparticles: In vitro characterization and in vivo pharmacokinetic study in rats
MK Anwer, M Mohammad, E Ezzeldin… - International journal …, 2019 - Taylor & Francis
Background Apremilast (APM) is a novel, orally administered small molecule drug approved
for treatment of psoriasis or psoriatic arthritis. Due to its low solubility and permeability, it is …
for treatment of psoriasis or psoriatic arthritis. Due to its low solubility and permeability, it is …
[HTML][HTML] Design of olmesartan medoxomil-loaded nanosponges for hypertension and lung cancer treatments
Olmesartan medoxomil (OLM) is one of the prominent antihypertensive drug that suffers from
low aqueous solubility and dissolution rate leading to its low bioavailability. To improve the …
low aqueous solubility and dissolution rate leading to its low bioavailability. To improve the …
Development and evaluation of PLGA polymer based nanoparticles of quercetin
Quercetin is the most abundant antioxidant found in the human diet. Low aqueous solubility
of quercetin limits its bioavailability and hence therapeutic effects. Therefore, the aim of the …
of quercetin limits its bioavailability and hence therapeutic effects. Therefore, the aim of the …
Nanostructured lipid carriers of olmesartan medoxomil with enhanced oral bioavailability
The current study explores the potential of nanostructured lipid carriers (NLCs) for oral
bioavailability enhancement of olmesartan medoxomil (OLM) by systemic design approach …
bioavailability enhancement of olmesartan medoxomil (OLM) by systemic design approach …
Response surface methodology and artificial neural network-based modeling and optimization of phosphatidylserine targeted nanocarriers for effective treatment of …
This study aimed to develop and evaluate phosphatidylserine (PS)-targeted nanoparticles
for efficient delivery of methotrexate to tumor sites. Therefore, methotrexate-loaded …
for efficient delivery of methotrexate to tumor sites. Therefore, methotrexate-loaded …
Sustained release and enhanced oral bioavailability of rivaroxaban by PLGA nanoparticles with no food effect
The purpose of the currents study was to enhance bioavailability of rivaroxaban (RXB) and
reduce the food effect. RXB loaded PLGA nanoparticles (RXB-PLGA-NPs) were prepared by …
reduce the food effect. RXB loaded PLGA nanoparticles (RXB-PLGA-NPs) were prepared by …
[HTML][HTML] Preparation, evaluation and bioavailability studies of eudragit coated PLGA nanoparticles for sustained release of eluxadoline for the treatment of irritable …
MK Anwer, R Al-Shdefat, E Ezzeldin… - Frontiers in …, 2017 - frontiersin.org
Eluxadoline is a newly approved orally administered drug used for the treatment of Irritable
Bowel Syndrome with Diarrhea. It is reported as a poorly water-soluble drug due to which its …
Bowel Syndrome with Diarrhea. It is reported as a poorly water-soluble drug due to which its …
Biodegradable synthetic polyesters in the technology of controlled dosage forms of antihypertensive drugs–the overview
M Bialik, M Kuras, M Sobczak… - Expert Opinion on Drug …, 2019 - Taylor & Francis
Introduction: Arterial hypertension is a disease of civilization that requires long-term
treatment. Recently, growing interest in natural and synthetic polymers as drug delivery …
treatment. Recently, growing interest in natural and synthetic polymers as drug delivery …
Enhanced oral bioavailability of ibrutinib encapsulated poly (lactic-co-glycolic acid) nanoparticles: Pharmacokinetic evaluation in rats
Background: The poor oral bioavailability of newly discovered chemical entities and
marketed formulations are usually related to poor aqueous solubility or poor permeability …
marketed formulations are usually related to poor aqueous solubility or poor permeability …