The bone microenvironment is an ideal fertile soil for both primary and secondary tumors to
seed. The occurrence and development of osteosarcoma, as a primary bone tumor, is …

Kaempferol, also known as kaempferol‑3 or kaempferide, is a flavonoid compound that
naturally occurs in tea, as well as numerous common vegetables and fruits, including beans …

Clinical outcomes and treatment modalities for osteosarcoma, the most common primary
cancer of bone, have changed very little over the past 30 years. The peak incidence of …

Importance Osteosarcoma, the most common malignant bone tumor in children and
adolescents, occurs in a high number of cancer predisposition syndromes that are defined …

Osteosarcoma is the most common primary bone tumor, yet there have been no substantial
advances in treatment or survival in three decades. We examined 59 tumor/normal pairs by …

Osteosarcoma is a malignant tumor that primarily affects the long bones but can also involve
other bones in the body. It has a bimodal distribution with peaks in the second decade of life …

Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Osteosarcomas are sarcomas of the bone, derived from osteoblasts or their precursors, with
a high propensity to metastasize. Osteosarcoma is associated with massive genomic …

Glioblastoma is the most common and most aggressive primary brain malignancy. The
current initial standard of care consists of maximal safe surgical resection followed by radical …

Osteosarcoma is the most common primary malignant bone tumor in children and young
adults. The standard-of-care curative treatment for osteosarcoma utilizes doxorubicin …