Monocytes, macrophages, dendritic cells and neutrophils: an update on lifespan kinetics in health and disease
Phagocytes form a family of immune cells that play a crucial role in tissue maintenance and
help orchestrate the immune response. This family of cells can be separated by their nuclear …
help orchestrate the immune response. This family of cells can be separated by their nuclear …
The HIV reservoir in monocytes and macrophages
ME Wong, A Jaworowski, AC Hearps - Frontiers in immunology, 2019 - frontiersin.org
In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
Systemic effects of inflammation on health during chronic HIV infection
Combination antiretroviral therapy for HIV infection improves immune function and
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
Central nervous system viral invasion and inflammation during acute HIV infection
V Valcour, T Chalermchai, N Sailasuta… - The Journal of …, 2012 - academic.oup.com
Background. Understanding the earliest central nervous system (CNS) events during human
immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but …
immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but …
Soluble CD163
HJ Møller - Scandinavian journal of clinical and laboratory …, 2012 - Taylor & Francis
CD163 is an endocytic receptor for haptoglobin-hemoglobin complexes and is expressed
solely on macrophages and monocytes. As a result of ectodomain shedding, the …
solely on macrophages and monocytes. As a result of ectodomain shedding, the …
Soluble CD163 made by monocyte/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy
TH Burdo, MR Lentz, P Autissier… - Journal of Infectious …, 2011 - academic.oup.com
CD163, a monocyte-and macrophage-specific scavenger receptor, is shed during activation
as soluble CD163 (sCD163). We have previously demonstrated that monocyte expansion …
as soluble CD163 (sCD163). We have previously demonstrated that monocyte expansion …
Soluble CD163, a novel marker of activated macrophages, is elevated and associated with noncalcified coronary plaque in HIV-infected patients
Background. Pro-inflammatory monocytes/macrophages may contribute to increased
atherosclerosis in human immunodeficiency virus (HIV)–infected patients. We investigate …
atherosclerosis in human immunodeficiency virus (HIV)–infected patients. We investigate …
Macrophages and their relevance in Human Immunodeficiency Virus Type I infection
H Koppensteiner, R Brack-Werner, M Schindler - Retrovirology, 2012 - Springer
Macrophages are important target cells for the Human Immunodeficiency Virus Type I (HIV-
1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type …
1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type …
Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection
Objective: Here we evaluated whether neurocognitive disorders in HIV-infected individuals
on effective antiretroviral therapy (ART) are associated with persistent monocyte activation …
on effective antiretroviral therapy (ART) are associated with persistent monocyte activation …
HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment
S Spudich, F González-Scarano - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
HIV-associated central nervous system (CNS) injury continues to be clinically significant in
the modern era of HIV infection and therapy. A substantial proportion of patients with …
the modern era of HIV infection and therapy. A substantial proportion of patients with …