Computational approaches for interpreting sc RNA‐seq data

R Rostom, V Svensson, SA Teichmann, G Kar - FEBS letters, 2017 - Wiley Online Library
The recent developments in high‐throughput single‐cell RNA sequencing technology (sc
RNA‐seq) have enabled the generation of vast amounts of transcriptomic data at cellular …

Oxidative stress and epigenetics: miRNA involvement in rare autoimmune diseases

JS Ibáñez-Cabellos, FV Pallardó, JL García-Giménez… - Antioxidants, 2023 - mdpi.com
Autoimmune diseases (ADs) such as Sjögren's syndrome, Kawasaki disease, and systemic
sclerosis are characterized by chronic inflammation, oxidative stress, and autoantibodies …

Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing

J Herrera-Uribe, JE Wiarda, SK Sivasankaran… - Frontiers in …, 2021 - frontiersin.org
Pigs are a valuable human biomedical model and an important protein source supporting
global food security. The transcriptomes of peripheral blood immune cells in pigs were …

Impact of sequencing depth and read length on single cell RNA sequencing data of T cells

S Rizzetto, AA Eltahla, P Lin, R Bull, AR Lloyd… - Scientific reports, 2017 - nature.com
Single cell RNA sequencing (scRNA-seq) provides great potential in measuring the gene
expression profiles of heterogeneous cell populations. In immunology, scRNA-seq allowed …

[HTML][HTML] Leukocyte diversity in resolving and nonresolving mechanisms of cardiac remodeling

B Tourki, G Halade - The FASEB Journal, 2017 - ncbi.nlm.nih.gov
In response to myocardial infarction (MI), time-dependent leukocyte infiltration is critical to
program the acute inflammatory response. Post-MI leukocyte density, residence time in the …

Jinglebells: a repository of immune-related single-cell rna–sequencing datasets

H Ner-Gaon, A Melchior, N Golan… - The Journal of …, 2017 - journals.aai.org
Recent advances in single-cell RNA–sequencing (scRNA-seq) technology increase the
understanding of immune differentiation and activation processes, as well as the …

[HTML][HTML] Exploring viral infection using single-cell sequencing

S Rato, M Golumbeanu, A Telenti, A Ciuffi - Virus research, 2017 - Elsevier
Single-cell sequencing (SCS) has emerged as a valuable tool to study cellular
heterogeneity in diverse fields, including virology. By studying the viral and cellular genome …

Multi-dimensional gene regulation in innate and adaptive lymphocytes: a view from regulomes

N Fernando, G Sciumè, JJ O'Shea… - Frontiers in immunology, 2021 - frontiersin.org
The precise control of cytokine production by innate lymphoid cells (ILCs) and their T cell
adaptive system counterparts is critical to mounting a proper host defense immune response …

[HTML][HTML] Genomic and transcriptomic approaches to study immunology in cyprinids: What is next?

J Petit, L David, R Dirks, GF Wiegertjes - Developmental & Comparative …, 2017 - Elsevier
Accelerated by the introduction of Next-Generation Sequencing (NGS), a number of
genomes of cyprinid fish species have been drafted, leading to a highly valuable collective …

Inkjet printing-assisted single-cell microarray on a hydrophobic surface chip for real-time monitoring of enzyme kinetics at single-cell level

X Lin, F Fang, C Wang, RK Kankala, S Zhou - Talanta, 2021 - Elsevier
A convenient, facile, and mask-free approach assay was developed for single-cell study by
using a combination of inkjet printing technology and polydimethylsiloxane (PDMS) …