[HTML][HTML] Defining the Differential Corticosteroid Response Basis from Multiple Omics Approaches

M Ramirez-Falcon, E Suarez-Pajes… - International Journal of …, 2024 - mdpi.com
Since their discovery, corticosteroids have been widely used in the treatment of several
diseases, including asthma, acute lymphoblastic leukemia, chronic obstructive pulmonary …

Endotypes of Paediatric Cough—Do They Exist and Finding New Techniques to Improve Clinical Outcomes

HE O'Farrell, HC Kok, S Goel, AB Chang… - Journal of Clinical …, 2024 - mdpi.com
Chronic cough is a common symptom of many childhood lung conditions. Given the
phenotypic heterogeneity of chronic cough, better characterization through endotyping is …

Progress in research on induced sputum in asthma: a narrative review

W Wei, Z Xie, J Yan, R Luo, J He - Journal of Asthma, 2024 - Taylor & Francis
Objective To explore the clinical significance of induced sputum in asthma through a
retrospective analysis of induced sputum in patients with asthma. Data sources The data …

Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022

D Stolz, MG Matera, P Rogliani, M van den Berge… - Breathe, 2023 - Eur Respiratory Soc
Pharmacological management of airway obstructive diseases is a fast-evolving field.
Several advances in unravelling disease mechanisms as well as intracellular and molecular …

Bei Mu Gua Lou San facilitates mucus expectoration by increasing surface area and hydration levels of airway mucus in an air-liquid-interface cell culture model of the …

S Groiss, I Somvilla, C Daxböck, M Stückler… - … Medicine and Therapies, 2023 - Springer
Abstract Background Bei Mu Gua Lou San (BMGLS) is an ancient formulation known for its
moisturizing and expectorant properties, but the underlying mechanisms remain unknown …

Meta-analysis of whole blood transcriptome datasets characterizes the immune response of respiratory syncytial virus infection in children

Q Feng, S Lin, H Liu, B Yang, L Han, X Han… - Frontiers in Cellular …, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) is the most common and critical viral pathogen causing
acute lower respiratory tract infection in infants and young children and has a huge disease …

Severity of lung function impairment drives transcriptional phenotypes of COPD and relates to immune and metabolic processes

NA Negewo, PG Gibson, JL Simpson… - … Journal of Chronic …, 2023 - Taylor & Francis
Purpose This study sought to characterize transcriptional phenotypes of COPD through
unsupervised clustering of sputum gene expression profiles, and further investigate …

Transcriptome-based Signatures: The Future Biomarkers in Obstructive Pulmonary Diseases Such as Asthma and Chronic Obstructive Pulmonary Disease?

M van den Berge, A Faiz - … Journal of Respiratory and Critical Care …, 2022 - atsjournals.org
In recent years, an increasing number of studies have applied wholetranscriptome profiling
to identify causal biological pathways and clinically relevant biomarkers. It has recently been …