Oncolytic vaccinia virus (VVs) based immunotherapy is a rapidly developing treatment for
gastrointestinal (GI) cancers. Conventional treatments, such as chemotherapy, radiotherapy …

Chemotherapy resistance and peculiar tumor microenvironment, which diminish or mitigate
the effects of therapies, make pancreatic cancer one of the deadliest malignancies to …

Immunotherapy is now a mainstay in cancer treatments. Programmed cell death 1 (PD-
1)/programmed cell death ligand 1 (PD-L1) immune checkpoint inhibitor (ICI) therapies have …

Oncolytic viruses have made a significant inroad in cancer drug development. Numerous
clinical trials are currently investigating oncolytic viruses both as single agents or in …

Abstract Development of successful cancer therapeutics requires exploration of the
differences in genetics, metabolism, and interactions with the immune system among …

In recent years, oncolytic viruses have emerged as promising agents for treating various
cancers. An oncolytic virus is a non-pathogenic virus that, due to genetic manipulation, tends …

Oncolytic viruses (OVs) possess the unique ability to selectively replicate within tumor cells,
leading to their destruction, while also reversing the immunosuppression within the tumor …

Simple Summary The tumor microenvironment (TME) plays a role in promoting tumor
progression. Elucidating the relationship between the TME and tumor cells will benefit …

胰腺神经内分泌肿瘤微环境是由肿瘤细胞, 免疫/免疫抑制细胞和细胞外基质成分等共同构建的
促癌微环境, 以免疫抑制为突出特征, 不仅可以抑制抗肿瘤免疫反应, 促进血管新生导致肿瘤细胞 …

The tumor microenvironment of pancreatic neuroendocrine tumor is a tumor-promoting
microenvironment composed of tumor cells, immune/immunosuppressive cells, and …