Surveying membrane landscapes: a new look at the bacterial cell surface

T Lithgow, CJ Stubenrauch, MPH Stumpf - Nature Reviews Microbiology, 2023 - nature.com
Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …

Macromolecular crowding, phase separation, and homeostasis in the orchestration of bacterial cellular functions

B Monterroso, W Margolin, AJ Boersma, G Rivas… - Chemical …, 2024 - ACS Publications
Macromolecular crowding affects the activity of proteins and functional macromolecular
complexes in all cells, including bacteria. Crowding, together with physicochemical …

Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane

S Manioglu, SM Modaresi, N Ritzmann, J Thoma… - Nature …, 2022 - nature.com
Polymyxins are last-resort antibiotics with potent activity against multi-drug resistant
pathogens. They interact with lipopolysaccharide (LPS) in bacterial membranes, but …

A periplasmic phospholipase that maintains outer membrane lipid asymmetry in Pseudomonas aeruginosa

RL Guest, MJ Lee, W Wang… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane of Gram-negative bacteria is unique in both structure and function. The
surface-exposed outer leaflet is composed of lipopolysaccharide, while the inner leaflet is …

Lipids mediate supramolecular outer membrane protein assembly in bacteria

MN Webby, AO Oluwole, C Pedebos, PG Inns… - Science …, 2022 - science.org
β Barrel outer membrane proteins (OMPs) cluster into supramolecular assemblies that give
function to the outer membrane (OM) of Gram-negative bacteria. How such assemblies form …

Function of the Omp85 superfamily of outer membrane protein assembly factors and polypeptide transporters

MT Doyle, HD Bernstein - Annual Review of Microbiology, 2022 - annualreviews.org
The Omp85 protein superfamily is found in the outer membrane (OM) of all gram-negative
bacteria and eukaryotic organelles of bacterial origin. Members of the family catalyze both …

[HTML][HTML] Lipopolysaccharides at solid and liquid interfaces: models for biophysical studies of the gram-negative bacterial outer membrane

N Paracini, E Schneck, A Imberty, S Micciulla - Advances in Colloid and …, 2022 - Elsevier
Lipopolysaccharides (LPSs) are a constitutive element of the cell envelope of Gram-
negative bacteria, representing the main lipid in the external leaflet of their outer membrane …

Terrabacteria: redefining bacterial envelope diversity, biogenesis and evolution

B Beaud Benyahia, N Taib, C Beloin… - Nature Reviews …, 2024 - nature.com
The bacterial envelope is one of the oldest and most essential cellular components and has
been traditionally divided into Gram-positive (monoderm) and Gram-negative (diderm) …

Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes

JBR White, A Silale, M Feasey, T Heunis, Y Zhu… - Nature, 2023 - nature.com
Bacteroidetes are abundant members of the human microbiota, utilizing a myriad of diet-and
host-derived glycans in the distal gut. Glycan uptake across the bacterial outer membrane of …

RNA origami: design, simulation and application

E Poppleton, N Urbanek, T Chakraborty, A Griffo… - RNA biology, 2023 - Taylor & Francis
Design strategies for DNA and RNA nanostructures have developed along parallel lines for
the past 30 years, from small structural motifs derived from biology to large …