Novel insights into NeuN: from neuronal marker to splicing regulator

W Duan, YP Zhang, Z Hou, C Huang, H Zhu… - Molecular …, 2016 - Springer
Neuronal nuclei (NeuN) is a well-recognized “marker” that is detected exclusively in post-
mitotic neurons and was initially identified through an immunological screen to produce …

Cell transplantation therapy for stroke

T Bliss, R Guzman, M Daadi, GK Steinberg - Stroke, 2007 - Am Heart Assoc
No treatment currently exists to restore lost neurological function after stroke. A growing
number of studies highlight the potential of stem cell transplantation as a novel therapeutic …

Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the …

J Lee, W Duan, MP Mattson - Journal of neurochemistry, 2002 - Wiley Online Library
To determine the role of brain‐derived neurotrophic factor (BDNF) in the enhancement of
hippocampal neurogenesis resulting from dietary restriction (DR), heterozygous BDNF …

[HTML][HTML] Potential of stem cell-based therapy for ischemic stroke

HE Marei, A Hasan - Frontiers in neurology, 2018 - frontiersin.org
Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-
thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several …

Cell based therapies for ischemic stroke: from basic science to bedside

X Liu, R Ye, T Yan, SP Yu, L Wei, G Xu, X Fan… - Progress in …, 2014 - Elsevier
Cell therapy is emerging as a viable therapy to restore neurological function after stroke.
Many types of stem/progenitor cells from different sources have been explored for their …

Optimizing the success of cell transplantation therapy for stroke

TM Bliss, RH Andres, GK Steinberg - Neurobiology of disease, 2010 - Elsevier
Stem cell transplantation has evolved as a promising experimental treatment approach for
stroke. In this review, we address the major hurdles for successful translation from basic …

Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral …

N Nakagomi, T Nakagomi, S Kubo, A Nakano-Doi… - Stem …, 2009 - academic.oup.com
Transplantation of neural stem cells (NSCs) has been proposed as a therapy for a range of
neurological disorders. To realize the potential of this approach, it is essential to control …

Human neural stem cells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia

K Chu, M Kim, SW Jeong, SU Kim, BW Yoon - Neuroscience letters, 2003 - Elsevier
Intraparenchymally transplanted rodent-origin neural and human-origin mesenchymal stem
cells migrate and differentiate in neurological diseases. By intravenously injecting human …

Neural stem cells improve memory in an inducible mouse model of neuronal loss

TR Yamasaki, M Blurton-Jones… - Journal of …, 2007 - Soc Neuroscience
Neuronal loss is a major pathological outcome of many common neurological disorders,
including ischemia, traumatic brain injury, and Alzheimer disease. Stem cell-based …

Application of stem cells in stroke: a multifactorial approach

M Singh, PK Pandey, A Bhasin, MV Padma… - Frontiers in …, 2020 - frontiersin.org
Stroke has a debilitating effect on the human body and a serious negative effect on society,
with a global incidence of one in every six people. According to the World Health …