Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic
alterations and degree of interaction with systemic hormones and metabolites. These …

Cancer is driven by incremental changes that accumulate, eventually leading to oncogenic
transformation. Although genetic alterations dominate the way cancer biologists think about …

Nutrition exerts considerable effects on health, and dietary interventions are commonly used
to treat diseases of metabolic aetiology. Although cancer has a substantial metabolic …

Glucose is vital for life, serving as both a source of energy and carbon building block for
growth. When glucose is limiting, alternative nutrients must be harnessed. To identify …

Cancer is a major disease with a high mortality rate worldwide. In many countries, cancer is
considered to be the second most common cause of death after cardiovascular disease. The …

Nutrients are indispensable resources that provide the macromolecular building blocks and
energy requirements for sustaining cell growth and survival. Cancer cells require several …

Malignant cells remodel their metabolism to meet the demands of uncontrolled cell
proliferation. These demands lead to differential requirements in energy, biosynthetic …

A high-sugar diet induces lifestyle-associated metabolic diseases, such as obesity and
diabetes, which may underlie the pro-tumor effects of a high-sugar diet. We supply GL261 …

How lifespan and body weight vary as a function of diet and genetic differences is not well
understood. Here we quantify the impact of differences in diet on lifespan in a genetically …

The climate crisis, coupled with the COVID‐19 pandemic and the Black Lives Matter
movement, are contributing to a shift in what people eat. For environmental sustainability …